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Membre du personnel

Olivier TOUSSAINT

Publications (109)

2009
Potential nanotoxicity in blood : Effects of engineered nanoparticles on human blood constituents, in Nanofac 2009
Julie LALOY, Catherine MARBEHANT, Severine ROBERT, François MULLIER, Bernard CHATELAIN, Jean-Michel DOGNÉ, Olivier TOUSSAINT, Bernard MASEREEL, Stéphanie ROLIN

Contributions à des ouvrages collectifs

2010
p38MAPK in the Senescence of Human and Murine Fibroblasts, in Advances in Experimental Medicine and Biology Review, volume 694, pp. 126-137
Florence CHAINIAUX-DEBACQ, Emmanuelle BOILAN, Jeremie DEDESSUS LE MOUTIER, Geoffroy WEEMAELS, Olivier TOUSSAINT
2002
Radicaux libres et antioxydants dans le vieillissement, in Gérontologie préventive. Eléments de prévention du vieillissement pathologique, pp. 35-49
Patrick DUMONT, Veronique ROYER, Christophe FRIPPIAT, Thierry PASCAL, José REMACLE, Olivier TOUSSAINT
2002
Vieillissement cellulaire et sénescence réplicative, in Gérontologie préventive, pp. 25-34
Patrick DUMONT, Florence CHAINIAUX-DEBACQ, Jean-François DIERICK, José REMACLE, Olivier TOUSSAINT
2000
Nutrition, vieillissement et modèles in vitro permettant de tester les effets à long terme potentiels d'additifs alimentaires en développement dans l'industrie agro-alimentaire, in L'impact de la nutrition sur la santé, pp. 79-86
Olivier TOUSSAINT, Pierre LEMAIRE, Patrick DUMONT, Jean-François DIERICK, Thierry PASCAL, Christophe FRIPPIAT, Florence CHAINIAUX-DEBACQ, Joao Pedro MAGALHAES, François ELIAERS, Anne-France DABEE, José REMACLE
2000
Transcriptome and proteome analysis in human senescent fibroblasts and fibroblasts undergoing premature senescence induced by repeated sublethal stresses, in Molecular and cellular gerontology, collection Annals of the New York academy of sciences, volume 908, pp. 302-305
Jean-François DIERICK, Thierry PASCAL, Florence CHAINIAUX-DEBACQ, François ELIAERS, José REMACLE, Peter Mose LARSEN, Peter ROEPSTORFF, Olivier TOUSSAINT
2000
Human diploid fibroblasts display a decreased level of c-fos mRNA at 72 hours after exposure to sublethal H2O2 stress, in Molecular and cellular gerontology, collection Annals of the New York academy of sciences, volume 908, pp. 306-309
Patrick DUMONT, Maggi BURTON, Qin CHEN, Christophe FRIPPIAT, Thierry PASCAL, Jean-François DIERICK, François ELIAERS, Florence CHAINIAUX-DEBACQ, José REMACLE, Olivier TOUSSAINT
2000
Stress-induced premature senescence: essence of life, evolution, stress, and aging, in Molecular and cellular gerontology, collection Annals of the New York academy of sciences, volume 908, pp. 85-98
Olivier TOUSSAINT, Patrick DUMONT, Jean-François DIERICK, Thierry PASCAL, Christophe FRIPPIAT, Florence CHAINIAUX-DEBACQ, Francis SLUSE, François ELIAERS, José REMACLE
1996
From molecular gerontology to healthy old age: research strategies, in Molecular gerontology, pp. 201-209
Olivier TOUSSAINT, Suresh RATTAN
1996
Cellular ageing, energy production and stress, in Vitality, mortality and aging, collection Vienna aging series, volume 5, pp. 167-172
José REMACLE, Olivier TOUSSAINT
1996
Stress and energy metabolism in age-related processes, in Molecular gerontology, pp. 87-109
Olivier TOUSSAINT, José REMACLE
1995
Bioenergetics of mitochondria determine cell survival in stressful conditions, in Thirty years of progress in mitochondrial bioenergetics and molecular biology, collection Progress in cell research, volume 5, pp. 237-241
P. CORBISIER, Olivier TOUSSAINT, José REMACLE
1995
Protective effect of Ginkgo biloba extract (EGb 761) and bilobalide against mortality and accelerated cellular aging under stressful conditions, in Effects of Ginkgo biloba extract (EGb 761) on aging and age-related disorders, collection Advances in Ginkgo biloba extract research, volume 4, pp. 1-16
Olivier TOUSSAINT, François ELIAERS, Andrée HOUBION, José REMACLE, K. DRIEU

Articles de périodique

2012
Quantification of nanoparticles in aqueous food matrices using Particle-Induced X-ray Emission: DOI 10.1007/s00216-012-5895-9, in Analytical and Bioanalytical Chemistry
Omar LOZANO GARCIA, Jorge Humberto MEJIA MENDOZA, Tijani TABARRANT, Bernard MASEREEL, Jean-Michel DOGNÉ, Olivier TOUSSAINT, Stephane LUCAS
2012
Are stirring and sonication pre-dispersion methods equivalent for in vitro toxicology evaluation of SiC and TiC?, in Journal of Nanoparticle Research, volume 14, issue 4
Jorge Humberto MEJIA MENDOZA, Vanessa VALEMBOIS, Jean-Pascal PIRET, Marijn VAN HUIS, Frans TICHELAAR, Bernard MASEREEL, Olivier TOUSSAINT, Joseph DELHALLE, Zineb MEKHALIF, Stephane LUCAS
2011
Development of a PIXE analysis method for the determination of the biopersistence of SiC and TiC nanoparticles in rat lungs, in Nanotoxicology, DOI: 10.3109/17435390.2011.572301
Omar LOZANO GARCIA, Jorge Humberto MEJIA MENDOZA, Bernard MASEREEL, Olivier TOUSSAINT, Dominique LISON, Stephane LUCAS
2011
Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls.- doi:10.1016/j.exger.2010.10.012, in Experimental Gerontology, volume 11, issue 46, pp. 257-264
Thi Kim Duy VO, Patrice GODARD, M. DE SAINT HUBERT, G. MORRHAYE, Florence CHAINIAUX-DEBACQ, C. SWINE, V. GEENEN, H.-J. MARTENS, Olivier TOUSSAINT
2011
Transcriptomic biomarkers of the response of hospitalized geriatric patients admitted with heart failure. Comparison with hospitalized geriatric patients with infectious diseases or hip fracture, in Mech Ageing Dev - doi:10.1016/j.mad.2011.02.002, volume 132, pp. 131-139
Thi Kim Duy VO, Marie DE SAINT HUBERT, Gabriel MORRHAYE, Patrice GODART, Vincent GEENEN, Henri J. MARTENS, Florence CHAINIAUX-DEBACQ, Christian SWINE, Olivier TOUSSAINT
2011
Pro-inflammatory effects of different MWCNTs dispersions in p16INK4A-deficient telomerase-expressing human keratinocytes but not in human SV-40 immortalized sebocytes - doi:10.3109/17435390.2011.558642, in Nanotoxicology - Early online, volume 1, issue 17
Sebastien VANKONINGSLOO, Jean-Pascal PIRET, Christelle SAOUT, Florence NOEL, Jorge Humberto MEJIA MENDOZA, Alain COQUETTE, Christos C. ZOUBOULIS, Joseph DELHALLE, Stephane LUCAS, Olivier TOUSSAINT
2011
Effects of the dispersion methods in Pluronic F108 on the size and the surface composition of MWCNTs and their implications in toxicology assessment, in Journal of Nanoparticule Research, volume 13, issue 2, pp. 655-667
Jorge Humberto MEJIA MENDOZA, Frans TICHELAAR, Christelle SAOUT, Olivier TOUSSAINT, Bernard MASEREEL, Zineb MEKHALIF, Stephane LUCAS, Joseph DELHALLE
2011
Validation of the calibrated thrombin generation test (cTGT) as the reference assay to evaluate the procoagulant activity of nanomaterials. doi: 10.3109/17435390.2011.569096, in Nanotoxicology
Julie LALOY, Severine ROBERT, Catherine MARBEHANT, François MULLIER, Jorge Humberto MEJIA MENDOZA, Jean-Pascal PIRET, Stephane LUCAS, Bernard CHATELAIN, Jean-Michel DOGNÉ, Olivier TOUSSAINT, Bernard MASEREEL, Stéphanie ROLIN
2011
Serum IL-6 and IGF-1 improve clinical prediction of functional decline after hospitalization in older patients , in Aging Clinical and Experimental Research - doi10.3275/7028, volume 23, issue 2, pp. 106-111
Marie DE SAINT HUBERT, Jacques JAMART, Gabriel MORRHAYE, Henri J. MARTENS, Vincent GEENEN, Thi Kim Duy VO, Olivier TOUSSAINT, Christian SWINE
2010
Eco-, geno- and human toxicology of bio-active nanoparticles for biomedical applications. , in Toxicology, volume 269, pp. 170-181
J. ROBBENS, C. VANPARYS, J. NOBELS, R. BLUST, K. VAN HOECKE, C. JANSSEN, K. DE SCHAMPHELAERE, Kathleen ROLAND, Gersande BLANCHARD, Frederic SILVESTRE, Virginie GILLARDIN, Patrick KESTEMONT, R. ANTONISSEN, Olivier TOUSSAINT, Christelle SAOUT, Sebastien VANKONINGSLOO, E. ALFARO-MORENO, P. HOE, L. GONZALES, P. DUBRUEL, P. TROISFONTAINE
2010
Transcriptomic biomarkers of the response of hospitalized geriatric patients with infectious diseases, doi:10.1186/1742-4933-7-9, in Immunity & Ageing, volume 7, issue 9
Thi Kim Duy VO, Patrice GODARD, Marie DE SAINT HUBERT, Gabriel MORRHAYE, Christian SWINE, Vincent GEENEN, Henri J MARTENS, Florence CHAINIAUX-DEBACQ, Olivier TOUSSAINT
2010
Serum N-glycan profile shift during human ageing, in Experimental Gerontology, volume 45, pp. 738-743
Valerie VANHOOREN, Sylviane DEWAELE, Claude LIBERT, Sebastiaan ENGELBORGHS, Peter Paul DE DEYN, Olivier TOUSSAINT, Florence CHAINIAUX-DEBACQ, Michel POULAIN, Youri GLUPZYNSKI, Claudio FRANCESCHI, Koos JASPERS, Ingrid VAN DER PLUIJM, Jan HOEIJMAKERS, Chen CHITTY
2010
Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite motif protein 29 as a survival factor, in PLoS ONE/ www.plosone.org/e10462, volume 5, issue 5
Veronique VALLERY, Nathalie BELOT, Marc DIEU, Edouard DELAIVE, Noelle NINANE, Catherine DEMAZY, Martine RAES, Michel SALMON, Yves POUMAY, Florence CHAINIAUX-DEBACQ, Olivier TOUSSAINT
2010
Physio-pathological parameters affect the activation of inflammatory pathways by deoxynivalenol in Caco-2 cells , in Toxicology in Vitro, volume 24, pp. 1890-1894
Jacqueline VAN DE WALLE, Alexandre DURING, Neil PIRONT, Olivier TOUSSAINT, Yves-Jacques SCHNEIDER, Yvan LARONDELLE
2010
Dispersion of multi-walled carbon nanotubes in biocompatible dispersants, in J. Nanoparts Res., volume 12, issue 1, pp. 75-82
Jean-Pascal PIRET, Simon DETRICHE, Renaud VIGNERON, Sebastien VANKONINGSLOO, Stéphanie ROLIN, Jorge Humberto MEJIA MENDOZA, Bernard MASEREEL, Stephane LUCAS, Joseph DELHALLE, Frédéric LUIZI, Christelle SAOUT, Olivier TOUSSAINT
2010
Deoxynivalenol affectsinvitrointestinal epithelial cell barrier integrity through inhibitionof proteinsynthesis, in Toxicology and Applied Pharmacology, volume 245, pp. 291-298
Jacqueline VAN DE WALLE, Thérèse SERGENT, Neil PIRONT, Olivier TOUSSAINT, Yves-Jacques SCHNEIDER, Yvan LARONDELLE
2010
Somatic point mutations in mtDNA control region are influenced by genetic background and associated with healthy aging: a GEHA study., in PlOS One, volume 10
G. ROSE ET AL (...), Olivier TOUSSAINT
2010
Artefactual Effects ofq1 Oxygen on Cell Culture Models of Cellular Senescence and Stem Cell Biology, in Journal of Cellular Physiology - DOI: 10.1002/jcp.22416 , pp. 315-321
Olivier TOUSSAINT, Geoffroy WEEMAELS, Florence CHAINIAUX-DEBACQ, K. SCHARFEFETTER-KOCHANEK, M. WLASCHEK
2010
Eco-, geno- and human toxicology of bio-active nanoparticles for biomedical applications, in Toxicology - doi:10.1016/j.tox.2009.11.002, pp. 170-181
J. ROBBENS ET AL (...), Kathleen ROLAND, Gersande BLANCHARD, Frederic SILVESTRE, Virginie GILLARDIN, Patrick KESTEMONT, Olivier TOUSSAINT, Sebastien VANKONINGSLOO, Christelle SAOUT
2010
Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16INK-4A , in Biogerontology, pp. 167-181
Veronique VALLERY, Emmanuelle BOILAN, Noelle NINANE, Catherine DEMAZY, B. FRIGUET, Olivier TOUSSAINT, Yves POUMAY, Florence CHAINIAUX-DEBACQ
2010
Effects of the dispersion methods in Pluronic F108 on the size and the surface composition of MWCNTs and their implications in toxicology assessment, in J Nanoparts Res, DOI 10 1007/s11051-010-0063-7
Jorge MEJIA, Frans TICHELAAR, Christelle SAOUT, Olivier TOUSSAINT, Bernard MASEREEL, Zineb MEKHALIF, Stephane LUCAS, Joseph DELHALLE
2010
Transcriptomic biomarkers of human ageing in peripheral blood monocluear cell total RNA, in Experimental Gerontology, volume 45, pp. 188-194
Thi Kim Duy VO, Patrice GODARD, Marie DE SAINT HUBERT, Gabriel MORRHAYE, Emilie BAUWENS, Florence CHAINIAUX-DEBACQ, Youri GLUPCZYNSKI, Christian SWINE, Vincent GENNEN, Henri J. MARTENS, Olivier TOUSSAINT
2010
Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium, in Chemico-Biological Interactions, volume 188, pp. 659-667
Thérèse SERGENT, Neil PIRONT, Julie MEURICE, Olivier TOUSSAINT, Yves-Jacques SCHNEIDER
2010
Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: Effects of sonication, dispersive agents and corneous layer of reconstructed epidermis - doi:10.3109/17435390903428869, in Nanotoxicology, volume 4, issue 1, pp. 84-97
Sebastien VANKONINGSLOO, Jean-Pascal PIRET, Christelle SAOUT, Florence NOEL, Joseph DELHALLE, Jorge Humberto MEJIA MENDOZA, Christos C. ZOUBOULIS, Stephane LUCAS, Olivier TOUSSAINT
2009
Age-related cellular copper dynamics in the fungal ageing model Podospora anserina and in ageing human fibroblasts, in Plos one, volume 4, issue 3, pp. 1-14
Christian Q. SCHECKHUBER, Jürgen GRIEF, Emmanuelle BOILAN, Karin LUCE, Florence CHAINIAUX-DEBACQ, Claudia RITTMEYER, Ricardo GREDILLA, Benrnd O. KOLBESEN, Olivier TOUSSAINT, Heinz D. OSIEWACZ
2009
p53 and ATF-2 partly mediate the overexpression of COX-2 in H2O2-induced premature senescence of human fibroblasts, in Biogerontology, volume 10, pp. 291-298
Stéphanie ZDANOV, Olivier TOUSSAINT, Florence CHAINIAUX-DEBACQ
2009
The development of nanotoxicity assays,... for regulatory purposes, in Public Service Review, Science and Technology, volume 4, pp. 1-2
Christelle SAOUT, Olivier TOUSSAINT
2009
Protocols to detect senescence-associated beta-galactosidase (SA-Βgal) activity, a biomarker of senescent cells in culture and in vivo, in Nature protocols, volume 4, issue 12, pp. 1798-1806
Florence CHAINIAUX-DEBACQ, Jorge ERUSALIMSKY, Judith CAMPISI, Olivier TOUSSAINT
2008
Biological models for phytochemical research: from cell to human organism, in British Journal of Nutrition, volume 99, issue E-Suppl 1, pp. 118-126
Alicja MORTENSEN, Ilona K. SORENSEN, Colin WILDE, Stefania DRAGONI, Dana MULLEROVA, Olivier TOUSSAINT, Zdenek ZLOCH, Giampietro SGARAGLI, Jaroslava OVESNA
2008
Role of TGF-⓵-independent changes in protein neosynthesis, p38αMAPK, and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis, in Free Radical Biology & Medicine, volume 44, issue 9, pp. 1732-1751
Aline CHRÉTIEN, Jean-François DIERICK, Edouard DELAIVE, Martin ROSSEL-LARSEN, Marc DIEU, Martine RAES, Christophe F. DEROANNE, Peter ROEPSTORFF, Olivier TOUSSAINT
2008
Replicative aging down-regulates the myogenic regulatory factors in human myoblasts, in Biol. Cell, volume 100, issue 3, pp. 189-199
Anne BIGOT, Virginie JACQUEMIN, Florence CHAINIAUX-DEBACQ, Gillian S. BUTLER-BROWNE, Olivier TOUSSAINT, Denis FURLING, Vincent MOULY
2008
Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts, in Free Radical Biology & Medicine, volume 44, pp. 1817-1832
Florence CHAINIAUX-DEBACQ, Thierry PASCAL, Emmanuelle BOILAN, Coralie BASTIN, Emilie BAUWENS, Olivier TOUSSAINT
2008
High throughput 'omics' approaches to assess the effects of phytochemicals in human health studies, in British Journal of Nutrition, volume 99, issue E-Suppl 1, pp. 130-137
Jaroslava OVESNA, Ondrej SLABY, Olivier TOUSSAINT, Milan KODICEK, Petr MARSIK, Vladimira POUCHOVA, Tomas VANEK
2008
Prematurely senescent ARPE-19 cells display features of age-related macular degeneration, in Free Radical Biology & Medicine, volume 44, pp. 1348-1361
Anne-Lise GLOTIN, Florence CHAINIAUX-DEBACQ, Jean-Yves BROSSAS, Anne-Marie FAUSSAT, Jacques TRETON, Anna ZUBIELEWICZ, Olivier TOUSSAINT, Frédéric MASCARELLI
2008
Upregulation of annexin A2 in H202-induced premature senescence as evidence by 2D-DIGE proteome analysis, in Experimental Gerontology, volume 43, pp. 353-359
Aline CHRÉTIEN, Edouard DELAIVE, Marc DIEU, Catherine DEMAZY, Noelle NINANE, Martine RAES, Olivier TOUSSAINT
2008
Identification of p53-dependent genes potentially involved in UVB-mediated premature senescence of human skin fibroblasts using siRNA technology, in Mechanisms of Ageing and Development, volume 129, issue 3, pp. 109-119
Celine BORLON, Sebastien VANKONINGSLOO, Patrice GODARD, Florence CHAINIAUX-DEBACQ, Olivier TOUSSAINT
2008
Increased abundance of cytoplasmic and nuclear caveolin 1 in human diploid fibroblast in H2O2-induced premature senescence and interplay with p38αMAPK, in FEBS letter, volume 582, issue 12, pp. 1685-1692
Aline CHRÉTIEN, Neil PIRONT, Edouard DELAIVE, Catherine DEMAZY, Noelle NINANE, Olivier TOUSSAINT
2008
Expression profiling of senescent-associated genes in human dermis from young and old donors: proof-of-concept study, in Biogerontology, volume 9, issue 3, pp. 197-208
Celine BORLON, Geoffroy WEEMAELS, Patrice GODARD, Florence CHAINIAUX-DEBACQ, Pierre LEMAIRE, Christophe DEROANNE, Olivier TOUSSAINT
2007
Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblast induced by tert-butylhydroperoxide and ethanol, in Biogerontology, volume 8, pp. 409-422
Thierry PASCAL, Florence CHAINIAUX-DEBACQ, Emmanuelle BOILAN, Noelle NINANE, Martine RAES, Olivier TOUSSAINT
2006
Identification of potential anti-photoageing algal compounds using an in-vitro model of photoageing, in Journal of Pharmacy and Pharmacology, volume 58, pp. 1577-1583
Florence CHAINIAUX-DEBACQ, Celine BORLON, Benoît DE HERTOGH, José REMACLE, P.-Y. MORVAN, R. VALLEE, Olivier TOUSSAINT
2006
Identification of p38(MAPK)-dependent genes with changed transcript abundance in H(2)O(2)-induced premature senescence of IMR-90 hTERT human fibroblasts, in FEBS Letters, volume 580, issue 27, pp. 6455-6463
Stéphanie ZDANOV, Florence CHAINIAUX-DEBACQ, José REMACLE, Olivier TOUSSAINT
2005
Informed consent of very old patients and modern genomics, in Biogerontology, volume 6, pp. 81-84
Eric MATTHEWS, Erica HAIMES, Anne-Marie DUGUET, Brian CLARK, Christian SWINE, Olivier TOUSSAINT
2005
HAGR- The human aging genomic ressources, in Nucleic Acids Research, volume 33, pp. D537-D547
JP DE MAGALHAES, J COSTA, Olivier TOUSSAINT
2005
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays, in FEBS Letters, volume 579, issue 17, pp. 3651-3659
Thierry PASCAL, Florence CHAINIAUX-DEBACQ, Aline CHRÉTIEN, Coralie BASTIN, Anne-France DABEE, Vincent BERTHOLET, José REMACLE, Olivier TOUSSAINT
2005
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-B1 signaling pathway, in Journal of Cell Science, volume 118, issue 4, pp. 743-758
Florence CHAINIAUX-DEBACQ, Celine BORLON, Thierry PASCAL, Veronique ROYER, François ELIAERS, Noelle NINANE, Géraldine CARRARD, Bertrand FRIGUET, Françoise DE LONGUEVILLE, Sophie BOFFE, José REMACLE, Olivier TOUSSAINT
2004
Gene expression and regulation in H2O2-induced premature senescence of human fibroblasts expressing or not telomerase, in Experimental Gerontology, volume 39, pp. 1379-1389
Joao Pedro DE MAGALHAES, Florence CHAINIAUX-DEBACQ, Françoise DE LONGUEVILLE, Véronique MAINFROID, Valérie MIGEOT, Laurence MARCQ, José REMACLE, Michel SALMON, Olivier TOUSSAINT
2004
How bioinformatics can help reverse engineer human aging, in Ageing Research Reviews, volume 3, pp. 125-141
Joao Pedro DE MAGALHAES, Olivier TOUSSAINT
2004
Role of the PLA2-independent peroxiredoxin VI activity in the survival of immortalized fibroblasts exposed to cytotoxic oxidative stress, in FEBS Letters, volume 557, pp. 26-32
Michel SALMON, Jeremie DEDESSUS LE MOUTIER, Frederic WENDERS, Sophie CHIARIZIA, François ELIAERS, José REMACLE, Veronique ROYER, Thierry PASCAL, Olivier TOUSSAINT
2003
Normal brain aging : a commentary, in Neurobiology of aging, volume 24, pp. 129-130
Olivier TOUSSAINT
2003
Impact of ageing on proteasome structure and function in human lymphocytes, in The international journal of Biochemistry & Cell biology, volume 35, pp. 728-739
Géraldine CARRARD, Marc DIEU, Martine RAES, Olivier TOUSSAINT, Bertrand FRIGUET
2003
View of a young biogerontologist on the in vitro biogerontological model systems, in Experimental Gerontology, volume 38, pp. 1229-1230
Olivier TOUSSAINT
2003
Retrovirally mediated overexpression of peroxiredoxin VI increases the survival of WI-38 human diploid fibroblasts exposed to cytotoxic doses of tert-butylhydroperoxide and UVB, in Biogerontology, volume 4, pp. 125-131
Jean-François DIERICK, Frederic WENDERS, Florence CHAINIAUX-DEBACQ, José REMACLE, Olivier TOUSSAINT, Aron FISHER
2003
Role of subcytotoxic stress in tissue ageing, in Topics in current genetics, volume 3, pp. 269-294
Olivier TOUSSAINT, Michel SALMON, Veronique ROYER, Jean-François DIERICK, Joao PEDRO DE MAGALHAES, Frederic WENDERS, Stéphanie ZDANOV, Aline CHRÉTIEN, Celine BORLON, Thierry PASCAL, Florence CHAINIAUX-DEBACQ
2002
Stress-induced premature senescence: from biomarkers to likeliness of in vivo occurrence, in Biogerontology, volume 3, pp. 13-17
Olivier TOUSSAINT, José REMACLE, Jean-François DIERICK, Thierry PASCAL, Christophe FRIPPIAT, Veronique ROYER, Joao Pedro MAGALHAES, Stéphanie ZDANOV, Florence CHAINIAUX-DEBACQ
2002
Radicaux libres et antioxydants dans le vieillissement, in Gérontologie préventive, pp. 35-49
Patrick DUMONT, Veronique ROYER, Christophe FRIPPIAT, Thierry PASCAL, José REMACLE, Olivier TOUSSAINT
2002
Proteomics in experimental gerontology, in Experimental gerontology, volume 37, pp. 721-734
Jean-François DIERICK, Marc DIEU, José REMACLE, Martine RAES, Peter ROEPSTORFF, Olivier TOUSSAINT
2002
Exposure of skin human diploid fibroblasts to repeated subcytotoxic doses of UVB induces the overexpression of the TGF-B1 mRNA, in NY Acad Sci, volume 973, pp. 44-48
Florence CHAINIAUX-DEBACQ, José REMACLE, Olivier TOUSSAINT
2002
From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing, in The International Journal of Biochemistry & Cell biology, volume 34, pp. 1415-1429
Olivier TOUSSAINT, José REMACLE, Jean-François DIERICK, Thierry PASCAL, Christophe FRIPPIAT, Stéphanie ZDANOV, Joao Pedro MAGALHAES, Veronique ROYER, Florence CHAINIAUX-DEBACQ
2002
Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts, in Free Radical biology & Medecine, volume 33, pp. 1334-1346
Christophe FRIPPIAT, Janique DEWELLE, José REMACLE, Olivier TOUSSAINT
2002
Identification of 30 protein species involved in replicative senescence and stress-induced premature senescence, in FEBS Letters, volume 531, pp. 499-504
Jean-François DIERICK, Dario E. KALUME, Frederic WENDERS, Michel SALMON, Marc DIEU, Martine RAES, Peter ROEPSTORFF, Olivier TOUSSAINT
2002
UVB-induced premature senescence of human diploid skin fibroblasts, in The International Journal of Biochemistry & Cell Biology, volume 34, pp. 1331-1339
Florence CHAINIAUX-DEBACQ, Joao-Pedro MAGALHAES, François ELIAERS, José REMACLE, Olivier TOUSSAINT
2002
Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts, in FEBS Letters, volume 523, pp. 157-162
Joao Pedro DE MAGALHAES, Florence CHAINIAUX-DEBACQ, José REMACLE, Olivier TOUSSAINT
2002
Stress-induced premature senescence and tissue ageing, in Biochemical Pharmacology, volume 64, pp. 1007-1009
Olivier TOUSSAINT, Veronique ROYER, Michel SALMON, José REMACLE
2002
Down-regulation and decreased activity of cyclin-dependent kinase 2 in H2O2-induced premature senescence, in The International Journal of Biochemestry & Cell Biology , volume 1361, pp. 1-9
Christophe FRIPPIAT, José REMACLE, Olivier TOUSSAINT
2002
Les mécanismes moléculaires et cellulaires du vieillissement humain, in Sport à 50 ans
Olivier TOUSSAINT, José REMACLE
2002
Stress, cells and tissue ageing, in Biology of Aging and its modulation, SIS Rattan, in press, volume 5, pp. 101-125
Jean-François DIERICK, Christophe FRIPPIAT, Florence CHAINIAUX-DEBACQ, Olivier TOUSSAINT
2002
Stress-induced premature senescence or stress-induced senescence-like phenotype: one in vivo reality, two posssible defintions? How stress, cellular behaviors, growth kinetics and cell heterogeneity interact in senescence, in The Scientific World Journal, volume 2, pp. 230-247
Olivier TOUSSAINT, Patrick DUMONT, José REMACLE, Jean-François DIERICK, Thierry PASCAL, Christophe FRIPPIAT, Joao Pedro MAGALHAES, Stéphanie ZDANOV, Florence CHAINIAUX-DEBACQ
2002
Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence, in Biochemical Pharmacology, volume 64, pp. 1011-1017
Jean-François DIERICK, François ELIAERS, José REMACLE, Martine RAES, Stephen J. FEY, Peter Mose LARSEN, Olivier TOUSSAINT
2002
Overexpression of apolipoprotein J in human fibroblasts protects against cyotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide, in Cell Stress & Chaperones , volume 7, pp. 23-35
Patrick DUMONT, Florence CHAINIAUX-DEBACQ, François ELIAERS, chariklia PETROPOULOU, José REMACLE, Claudia KOCH-BRANDT, Efstathios S. GONOS, Olivier TOUSSAINT
2002
Approach of evolutionary theories of ageing, stress, senescence-like phenotypes, calorie restriction and hormesis from the view point of far-from-equilibrium thermodynamics, in Mechanisms of Ageing and Development, volume 123, pp. 937-946
Olivier TOUSSAINT, José REMACLE, Jean-François DIERICK, Thierry PASCAL, Christophe FRIPPIAT, Veronique ROYER, Florence CHAINIAUX-DEBACQ
2002
The evolution of mammalian aging, in Experimental Gerontology, volume 37, pp. 769-775
Joao Pedro de MAGALHAES, Olivier TOUSSAINT
2001
Subcytotoxic H2O2 stress triggers a release of transforming growth factor-β 1, which induces biomarkers of cellular senescence of human diploid fibroblasts, in Journal of Biological Chemistry, volume 276, issue 4, pp. 2531-2537
Christophe FRIPPIAT, Qin CHEN, Stephanie ZDANOV, Joao-Padro MAGALHAES, José REMACLE, Olivier TOUSSAINT
2000
Appearance of biomarkers of in vitro ageing after successive stimulation of WI-38 fibroblasts with IL-1α and TNF-α: senescence associated β-galactosidase activity and morphotype transition, in Journal of Anatomy, volume 197, pp. 529-537
Patrick DUMONT, Laura BALBEUR, José REMACLE, Olivier TOUSSAINT
2000
Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast, in Free Radical Biology and Medicine, volume 28, issue 3, pp. 361-373
Patrick DUMONT, Maggi BURTON, Qin CHEN, Efstathios GONOS, Christophe FRIPPIAT, Jean-Baptiste MAZARATI, François ELIAERS, José REMACLE, Olivier TOUSSAINT
2000
Cell cycle regulation in H2O2-induced premature senescence of human diploid fibroblasts and regulatory control exerted by the papilloma virus E6 and E7 proteins, in Experimental Gerontology, volume 35, pp. 733-745
Christophe FRIPPIAT, Qin CHEN, José REMACLE, Olivier TOUSSAINT
2000
Experimental gerontology in Belgium: from model organisms to age-related pathologies, in Experimental Gerontology, pp. 901-916
Olivier TOUSSAINT, BARET, BRION, CRAS, COLLETTE, DE DEYN, GEENEN, KIENLEN-CAMPARD, LABEUR, LEGROS, NÈVE, OCTAVE, PIÉRARD, SALMON, VAN DEN BOSCH DE AGUILAR, VAN DER LINDEN, LEUVEN, VANFLETEREN
2000
Cellular and molecular mechanisms of stress-induced premature senescece (SIPS) of human diploid fibroblasts and melanocytes, in Experimental Gerontology, pp. 927-945
Olivier TOUSSAINT, MEDRANO, VON ZGLINICKY
2000
Biology of ageing, in BioESsays, volume 22, pp. 954-956
Olivier TOUSSAINT, José REMACLE, Brian F.C. CLARK, Efstathios S. GONOS, Claudio FRANCESCHI, Thomas B.L. KIRKWOOD
2000
Stress-induced premature senescence as alternative toxicological method for testing the long-term effects of molecules under development in the industry, in Biogerontology, volume 1, pp. 177-181
Olivier TOUSSAINT, Patrick DUMONT, Jean-François DIERICK, Thierry PASCAL, Christophe FRIPPIAT, Florence CHAINIAUX-DEBACQ, Joao-Pedro MAGALHAES, François ELIAERS, José REMACLE
2000
Consideration of heteroduplexes and homoduplexes for the quantification by competitive PCR of human mitochondrial DNA deletions with ageing of tissues and cells, in Biogerontology, volume 1, pp. 279-283
Christophe FRIPPIAT, Jean-François DIERICK, José REMACLE, Olivier TOUSSAINT
2000
Molecular and cellular gerontology, in EMBO J., volume 19, pp. 1929-1934
Christine BRACK, Gordon LITHGOW, Olivier TOUSSAINT, OZIEWACZ
1998
La réponse des cellules aux stress: relation avec le processus de vieillissement et la pathologie, in M/S: médecine/sciences, volume 14, issue 5, pp. 622-635
Olivier TOUSSAINT, Martine RAES, Carine MICHIELS, José REMACLE
1998
Reciprocal relationships between the resistance to stresses and cellular aging, in Annals of the New York academy of sciences, volume 851, pp. 450-465
Olivier TOUSSAINT, Serge Y. FUCHS, Ze'Ev A. RONAI, Shogen ISOYAMA, Nitta YUKO, Valeria PETRONILLI, Paolo BERNARDI, Efstathios S. GONOS, Patrick DUMONT, José REMACLE
1998
Stress, aging, and neurodegenerative disorders: molecular mechanisms, in Annals of the New York academy of sciences, volume 851, pp. 429-443
Jorge BUSCIGLIO, Julie K. ANDERSEN, Hyman M. SCHIPPER, Gad M. GILAD, Richard MCCARTY, Fulvio MARZATICO, Olivier TOUSSAINT
1998
The thermodynamics and evolution of complexity in biological systems, in Comparative biochemistry and physiology. Part A, issue 120, pp. 3-9
Olivier TOUSSAINT, Eric D. SCHNEIDER
1996
Mathematical model of the survival curves and of the recovery times for mitosis of cell populations exposed to stresses
José REMACLE, Dominique LAMBERT, Olivier TOUSSAINT
1996
"Mathematical model of the survival curves and of the recovery times for mitosis of cell populations exposed to stresses", In vitro toxicology, 9 (1996) 251-259.
Dominique LAMBERT, Olivier TOUSSAINT, José REMACLE
1995
Low levels of reactive oxygen species as modulators of cell function, in Mutation research, issue 316, pp. 103-122
José REMACLE, Martine RAES, Olivier TOUSSAINT, Patricia RENARD, Govind RAO
1995
Cellular aging and the importance of energetic factors, in Experimental gerontology, volume 30, issue 1, pp. 1-22
Olivier TOUSSAINT, Carine MICHIELS, Martine RAES, José REMACLE
1993
O.TOUSSAINT, D.LAMBERT, J.REMACLE, "Mathematical modelling of the survival curves and of the recovery times of mitosis for cell populations exposed to chemicals", Arch. Int. Physiol. Biochem. Biophys., 101 B (1993) 86.
Olivier TOUSSAINT, Dominique LAMBERT, José REMACLE
1993
"Modelling of the transition between the different fibroblast morphotypes in vitro as a function of the time and of the stress intensity using a Markow process",: Arch. Int. Physiol. Biochem. Biophys., 101 B (1993) 45.
Dominique LAMBERT, Olivier TOUSSAINT, José REMACLE

Actes de colloques

2008
Risk assessment of nanoparticles on human health using in vitro models : a preliminary study, in 4th international congress of nanotechnology & clean tech 2007
Jean-Pascal PIRET, Sebastien VANKONINGSLOO, Renaud VIGNERON, Stéphanie ROLIN, Christelle SAOUT, Bernard MASEREEL, Joseph DELHALLE, Stephane LUCAS, Olivier TOUSSAINT
2008
Nanotoxico: Toxicological assessment of engineered nanoparticles using in vitro and in vivo models.
Stéphanie ROLIN, Bernard MASEREEL, Sebastien VANKONINGSLOO, Jean-Pascal PIRET, Stephane LUCAS, Olivier TOUSSAINT

Comptes rendus scientifiques

2010
The calibrated thrombin generation test (cTGT) : a gold standard assay to assess the procoagulant activity of nanomaterials, in 50) NARILIS symposium. Faculté de Médecine. FUNDP Namur. October 23th, 2010
Julie LALOY, Severine ROBERT, Catherine MARBEHANT, François MULLIER, Jorge Humberto MEJIA MENDOZA, Jean-Pascal PIRET, Joseph DELHALLE, Stephane LUCAS, Bernard CHATELAIN, Jean-Michel DOGNÉ, Olivier TOUSSAINT, Bernard MASEREEL, Stéphanie ROLIN
2009
Potential nanotoxicity in blood : Effects of engineered nanoparticles on human blood constituents, in Nanofac 2009
Julie LALOY, Catherine MARBEHANT, Severine ROBERT, François MULLIER, Bernard CHATELAIN, Jean-Michel DOGNÉ, Olivier TOUSSAINT, Bernard MASEREEL, Stéphanie ROLIN
2002
Reponse à long terme aux stress sublatéraux = vieillissement cellulaire accéléré, in Proceedings of 21st winter meeting : Gerontoly and Geriatry, pp. 23-38
Olivier TOUSSAINT, Patrick DUMONT, Thierry PASCAL, Jean-François DIERICK, Jean-Baptiste MAZARATI, Aurore BAREZ, François ELIAERS