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FUNDP > Faculty of Medicine > Department of Pharmacy

Publications (365)

2009
Potential nanotoxicity in blood : Effects of engineered nanoparticles on human blood constituents, in Nanofac 2009
Julie LALOY, Catherine MARBEHANT, Severine ROBERT, François MULLIER, Bernard CHATELAIN, Jean-Michel DOGNÉ, Olivier TOUSSAINT, Bernard MASEREEL, Stéphanie ROLIN

Serial

Collective work contributions

2007
Chap1. Anatomie pathologique macroscopique et microscopique. in Partie 8. Techniques de laboratoire, in Traité de Médecine Légale - Beauthier-, pp. 565-602
MD PIERCECCHI-MARTI, I SALMON, K MICHAUD, K DELBECQUE, P MANGIN, Stéphanie ROLIN, F BEAUTHIER, JP BEAUTHIER

Papers

2012
Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase, in Proceedings of the National Academy of Sciences, PNAS 2012 ; published ahead of print January 30, 2012, doi:10.1073/pnas.1113873109
Luc PILOTTE, Pierre LARRIEU, Vincent STROOBANT, Didier COLAU, Eduard DOLUSIC, Raphael FRÉDÉRICK, Etienne DE PLAEN, Catherine UYTTENHOVE, Johan WOUTERS, Bernard MASEREEL, Benoit VAN DEN EYNDE
2012
Discovery of pyrazolo[1,5-a]pyridines as p110alpha-selective PI3 kinase inhibitors., in Bioorganic and Medicinal Chemistry, volume 20, issue 1, pp. 69-85
J KENDALL, PD O'CONNOR, AJ MARSHALL, Raphael FRÉDÉRICK, ES MARSHALL, CL LILL, WJ LEE, S KELEKAR, M CHAO, A MALIK, S YU, C CHAUSSADE, C BUCHANAN, GW REWCASTLE, BC BAGULEY, JU FLANAGAN, SM JAMIESON, WA DENNY, PR SHEPHERD
2012
Novel pyrazolo[1,5-a]pyridines as p110alpha-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR., in Bioorganic and Medicinal Chemistry, volume 20, issue 1, pp. 58-68
J KENDALL, A GIDDENS, KY TSANG, Raphael FRÉDÉRICK, ES MARSHALL, R SINGH, CL LILL, WJ LEE, S KOLEKAR, M CHAO, A MALIK, S YU, C CHASSUADE, C BUCHANAN, GW REWCASTLE, BC BAGULEY, JU FLANAGAN, SM JAMIESON, WA DENNY, PR SHEPHERD
2011
Synthesis and biological evaluation of novel analogues of the pan Class I phosphatidylinositol 3-kinase (PI3K) inhibitor 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474), in J Med Chem, volume 54, issue 20, pp. 7105-7126
Gordon REWCASTLE, Swarna GAMAGE, Jack FLANAGAN, Raphael FRÉDÉRICK, William DENNY, Bruce BAGULEY, Phil KESTELL, R SINGH, Jackie KENDALL, Elaine MARSHALL, C LILL, W LEE, S KOLEKAR, C BUCHANAN, S JAMIESON, Peter SHEPHERD
2011
Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal CaCo-2 cells is correlated to copper release and specific area/shape. Comparison to multi-walled carbon nanotubes, in Nanotoxicology
Jean-Pascal PIRET, Sebastien VANKONINGSLOO, Jorge Humberto MEJIA MENDOZA, Nicolas NOEL, Emmanuelle BOILAN, Françoise LAMBINON, Bernard MASEREEL, Joseph DELHALLE, Stephane LUCAS, Christelle SAOUT, Marie-Christine JACQUES-TOUSSAINT
2011
Development of a PIXE analysis method for the determination of the biopersistence of SiC and TiC nanoparticles in rat lungs, in Nanotoxicology
Omar LOZANO GARCIA, Jorge Humberto MEJIA MENDOZA, Bernard MASEREEL, Olivier TOUSSAINT, Dominique LISON, Stephane LUCAS
2011
Validation of the calibrated thrombin generation test (cTGT) as the reference assay to evaluate the procoagulant activity of nanomaterials. doi: 10.3109/17435390.2011.569096, in Nanotoxicology
Julie LALOY, Severine ROBERT, Catherine MARBEHANT, François MULLIER, Jorge Humberto MEJIA MENDOZA, Jean-Pascal PIRET, Stephane LUCAS, Bernard CHATELAIN, Jean-Michel DOGNÉ, Olivier TOUSSAINT, Bernard MASEREEL, Stéphanie ROLIN
2011
BM-573 inhibits the development of early atherosclerotic lesions in Apo E deficient mice by blocking TP receptors and thromboxane synthase. doi: 10.1016/j.prostaglandins.2011.03.001, in Prostaglandins and Other Lipid Mediators
Céline CHERDON, Stéphanie ROLIN, Julien HANSON, OOMS, Laurence DE LEVAL, Pierre DRION, Marcelle MICHIELS, Bernard PIROTTE, Bernard MASEREEL, SAKALIHASSAN, DEFRAIGNE, Jean-Michel DOGNÉ
2011
Discovery and preliminary SARs of Keto-Indoles as Novel Indoleamine 2,3-Dioxygenase (IDO) Inhibitors, in European Journal of Medicinal Chemistry, volume 46, issue 7, pp. 3058-3065
Eduard DOLUSIC, Pierre LARRIEU, Sébastien BLANC, Frédéric SAPUNARIC, Jenny POUYEZ, Laurence MOINEAUX, Delphine COLETTE, Vincent STROOBANT, Luc PILOTTE, Didier COLAU, Thierry FERAIN, Graeme FRASER, Moreno GALLENI, Jean-Marie FRÈRE, Bernard MASEREEL, Benoît VAN DEN EYNDE, Johan WOUTERS, Raphael FRÉDÉRICK
2011
Tryptophan 2,3-dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators, in Journal of Medicinal Chemistry, volume 54, issue 15, pp. 5320-5334
Eduard DOLUSIC, Pierre LARRIEU, Laurence MOINEAUX, Vincent STROOBANT, Luc PILOTTE, Didier COLAU, Lionel POCHET, Benoît VAN DEN EYNDE, Bernard MASEREEL, Johan WOUTERS, Raphael FRÉDÉRICK
2011
Synthesis and evaluation of β-carboline derivatives as potential monoamine oxidase inhibitors, in Bioorganic & medicinal chemistry, volume 19, pp. 134-144
Jérémy RENIERS, Severine ROBERT, Raphael FRÉDÉRICK, Bernard MASEREEL, Stephane VINCENT, Johan WOUTERS
2011
Erythroblastopénie, in Feuillets de Biologie, volume LII, issue 298
François MULLIER, Elisabeth MOURIN, Christian CHATELAIN, Andre BOSLY, Bernard CHATELAIN
2011
Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors, in Bioorganic & Medicinal Chemistry, volume 19, issue 4, pp. 1550-1561
Eduard DOLUSIC, Pierre LARRIEU, Sébastien BLANC, Frédéric SAPUNARIC, Bernadette NORBERG, Laurence MOINEAUX, Delphine COLETTE, Vincent STROOBANT, Luc PILOTTE, Didier COLAU, Thierry FERAIN, Graeme FRASER, Moreno GALLENI, Jean-Marie FRÈRE, Bernard MASEREEL, Benoît VAN DEN EYNDE, Johan WOUTERS, Raphael FRÉDÉRICK
2010
Effects of leaf extracts from Croton zambesicus Muëll. Arg. on hemostasis, in Journal of Ethnopharmacology, volume 128, issue 3, pp. 641-648
Severine ROBERT, Chiara BACCELLI, Philippe DEVEL, Jean-Michel DOGNÉ, Joëlle QUETIN-LECLERCQ
2010
Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins, in Journal of Medicinal Chemistry, volume 53, pp. 335-344
Alfonso MARESCA, Claudia TEMPERINI, Lionel POCHET, Bernard MASEREEL, Andrea SCOZZAFAVA, Claudiu SUPURAN
2010
Design, solid-phase synthesis and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors, in Bioorganic and Medicinal Chemistry, volume 18, issue 21, pp. 7392-7401
Sébastien GLUSZOK, Raphael FRÉDÉRICK, Catherine FOULON, Frédérique KLUPSCH, Claudiu SUPURAN, Daniela VULLO, Andrea SCOZZAFAVA, Jean-François GOOSSENS, Bernard MASEREEL, Patrick DEPREUX, Laurence GOOSSENS
2010
Pyrazolo[4,3-c]isoquinolines as potential inhibitors of NK-κB activation, in Biochemical pharmacology, volume 79, pp. 1462-1472
Jérémie MORTIER, Raphael FRÉDÉRICK, Corinne GANEFF, Caroline REMOUCHAMPS, Patrice TALAGA, Lionel POCHET, Johan WOUTERS, Jacques PIETTE, Emmanuel DEJARDIN, Bernard MASEREEL
2010
Erythroblastopénie (Pure Red Cell Aplasia) . Louvain Médical Janvier 2010
Elisabeth MOURIN, François MULLIER, Christian CHATELAIN, Bernard CHATELAIN, André BOSLY
2010
Contribution of Platelet Microparticles Generation Assay to the Diagnosis of Type II Heparin-induced Thrombocytopenia. , in Thrombosis and Haemostasis, volume 103, issue 6, pp. 1277-1281
François MULLIER, Nicolas BAILLY, Yvan CORNET, Severine ROBERT, Eric DUBUC, Jean-Claude OSSELAER, Christian CHATELAIN, Jean-Michel DOGNÉ, Bernard CHATELAIN
2010
Antibody immobilization on gold nanoparticles coated layer-by-layer with polyelectrolytes (http://dx.doi.org/10.1007/s11051-010-9908-3), in Journal of Nanoparticle Research, volume 13, issue 4, pp. 1573-1580
Bernard MASEREEL, Mustapha DINGUIZLI, Nicolas MONIOTTE, Caroline BOUZIN, Olivier FERON, Bernard GALLEZ, Thierry VAN DER BORGHT, Carine MICHIELS, Stephane LUCAS
2009
2009
Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors, in Bioorganic and Medicinal Chemistry, volume 17, pp. 553-557
Anne THIRY, Marie LEDECQ, Alessandro CECCHI, Raphael FRÉDÉRICK, Jean-Michel DOGNÉ, Johan WOUTERS, Bernard MASEREEL, Claudiu T. SUPURAN
2009
Real-Time PCR in diagnosis of alpha-thalassemias: a future alternative? BIOTRIBUNE 2009 ; 32 : 25-28
Hassan MEKOUAR, Caroline DEBECKER, François MULLIER, Isabelle DERCLAYE, Jean-Luc VAERMAN, Marianne PHILIPPE
2009
Ir-CPI, a coagulation contact phase inhibitor from the hard tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis. , in Journal of Experimental Medecine, volume 206, issue 11, pp. 2381-2395
Yves DECREM, Géraldine RATH, Virginie BLASIOLI, Philippe CAUCHIE, Severine ROBERT, Jérôme BEAUFAYS, Jean-Marie FRÈRE, Jean-Michel DOGNÉ, Chantale DESSY, Luc VANHAMME, Edmond GODFROID
2009
Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors, in European journal of medicinal chemistry, volume 44, pp. 511-518
Anne THIRY, Aurélie DELAYEN, Laurence GOOSSENS, Raymond HOUSSIN, Marie LEDECQ, Aurélie FRANKART, Jean-Michel DOGNÉ, Johan WOUTERS, Claudiu T. SUPURAN, Jean-Pierre HENICHART, Bernard MASEREEL
2009
Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model, in Radiotherapy and oncology - accepted
Ludwig DUBOIS, Natasja G. LIEUWES, Alfonso MARESCA, Anne THIRY, Claudiu T. SUPURAN, Andrea SCOZZAFAVA, Bradly G. WOUTERS, Philippe LAMBIN
2009
Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs?, in Pharmacological Research, volume 59, issue 3, pp. 160-166
Severine ROBERT, Jérémie GHIOTTO, Bernard PIROTTE, Jean-Louis DAVID, Bernard MASEREEL, Lionel POCHET, Jean-Michel DOGNÉ
2008
Carbonic anhydrase inhibitors: Bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII, in Journal of Medicinal Chemistry, volume 51, issue 11, pp. 3230-3237
Katia D'AMBROSIO, Rosa-Maria VITALE, Jean-Michel DOGNÉ, Bernard MASEREEL, Alessio INNOCENTI, Andréa SCOZZAFAVA, Giuseppina DE SIMONE, Claudiu SUPURAN
2008
Production and preliminary characterization of DC plasma polymerized allylamine film (PPAA) by NRA, ERD, and XPS, in Nuclear instruments and methods in physics research. B, volume 266, pp. 2494-2497
Stephane LUCAS, Gilles GENARD, Carine MICHIELS, Bernard MASEREEL, Olivier FERON, Bernard GALLEZ, Thierry VANDER BORGHT, Nicolas MOREAU
2008
Carbonic anhydrase inhibitors: Binding of indanesulfonamides to the human isoform II, in ChemMedChem, volume 3, issue 3, pp. 473-477
Katia D'AMBROSIO, Bernard MASEREEL, Anne THIRY, Andréa SCOZZAFAVA, Claudiu SUPURAN, Giuseppina DE SIMONE
2008
Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors, in Journal of Medicinal Chemistry, volume 51, pp. 3077-3081
Severine ROBERT, Carine BERTOLLA, Bernard MASEREEL, Jean-Michel DOGNÉ, Lionel POCHET
2008
Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation, in European journal of medicinal chemistry, volume 43, pp. 2853-2860
Anne THIRY, Stéphanie ROLIN, Daniela VULLO, Aurélie FRANKART, Andrea SCOZZAFAVA, Jean-Michel DOGNÉ, Johan WOUTERS, Claudiu T. SUPURAN, Bernard MASEREEL
2007
Cardiovascular Hemodynamics and Ventriculo-Arterial Coupling in an Acute Pig Model of Ischemia-Reperfusion., in Experimental Physiolology, volume 92, issue 1, pp. 127-137
Lieve LANOYE, Patrick SEGERS, Vincent TCHANA-SATO, Stéphanie ROLIN, Jean-Michel DOGNÉ, Alexandre GHUYSEN, Bernard LAMBERMONT, Julien HANSON, Thomas DESAIVE, Vincent D'ORIO, Philippe KOLH
2007
Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX and XIV with sulfonamides incorporating fructopyranose-thioureido tails, in Bioorganic and Medicinal Chemistry Letters, volume 17, issue 10, pp. 2685-2691
Jean-Yves WINUM, Anne THIRY, Khaled EL CHEIKH, Jean-Michel DOGNÉ, Jean-Louis MONTERO, Daniela VULLO, Andrea SCOZZAFAVA, Bernard MASEREEL, Claudiu T. SUPURAN
2007
Dual carbonic anhydrase - Cyclooxygenase-2 inhibitors, in Current Topics in Medicinal Chemistry, volume 7, issue 9, pp. 885-891
Jean-Michel DOGNÉ, Anne THIRY, Domenico PRATICO, Bernard MASEREEL, Claudiu T. SUPURAN
2007
Radioimmunotherapy with radioactive nanoparticles: first results of dosimetry for vascularised and necrosed solid tumors, in Medical physics, volume 34, issue 11, pp. 4504-4513
Virginie BOUCHAT, Vincent NUTTENS, Carine MICHIELS, Bernard MASEREEL, Olivier FÉRON, Bernard GALLEZ, Thierry VANDER BORGHT, Stephane LUCAS
2006
Synthesis, structural reassignment and biological activity of type B MAO inhibitors based on the 5H-indeno-[1,2-c]pyridazin-5-one core, in Journal of Medicinal Chemistry, volume 49, issue 12, pp. 3743-3747
Raphael FRÉDÉRICK, Willy DUMONT, Frederic OOMS, Cornelis VAN DER SCHYF, Lindsey ASCHENBACH, Neal CASTAGNOLI, Johan WOUTERS, Alain KRIEF
2006
Synthesis, molecular modelling and enzymatic evaluation of (±) 3,5-diphenyl-2-thioxoimidazolidin-4-ones as new potential cyclooxygenase inhibitors, in Bioorganic and Medicinal Chemistry, volume 14, issue 4, pp. 918-927
Marie-Pierre GAUTHIER, Catherine MICHAUX, Stéphanie ROLIN, Caroline VASTERSAEGHER, Xavier DE LEVAL, Fabien JULÉMONT, Lionel POCHET, Bernard MASEREEL
2006
Evaluation of BM-573, a novel TXA2 synthase inhibitor and receptor antagonist, in a porcine model of myocardial ischemia-reperfusion, in Prostanglandins and Other Lipid Mediators, volume 79, issue 1-2, pp. 53-73
Philippe KOLH, Stéphanie ROLIN, Vincent TCHANA-SATO, Michel PÉTEIN, Alexandre GHUYSEN, Bernard LAMBERMONT, Julien HANSON, David MAGIS, Patrick SEGERS, Bernard MASEREEL, Vincent D'ORIO, Jean-Michel DOGNÉ
2005
A model of porcine myocardial-infarction induced by progressive coronary-artery thromobosis provoked by ferric-chlorade, in Hypertension, volume 46, pp. 911-911
Jean-Michel DOGNÉ, Stéphanie ROLIN, V TCHANA-SATO, M PETEIN, A GHUYSEN, B LAMBERMONT, J HANSON, V DORIO, R LIMET, P KOLH
2005
3,6-disubstituted coumarins as mechanism based inhibitors of Thrombin and Factor Xa, in Journal of Medicinal Chemistry, volume 48, pp. 7592-7603
Raphael FRÉDÉRICK, Severine ROBERT, Caroline CHARLIER, Jerome DE RUYCK, Johan WOUTERS, Bernard PIROTTE, Bernard MASEREEL, Lionel POCHET
2005
Effects of reperfusion on left ventricular hemodynamics and ventriculo-arterial coupling in acutely ischemic pigs, in Computer Methods in Biomechanics and Biomedical Engeineering, volume 8, pp. 169-170
Lieve LANOYE, Philippe KOLH, Stéphanie ROLIN, Vincent TCHANA-SATO, Jean-Michel DOGNÉ, Alexandre GHUYSEN, Bernard LAMBERMONT, David MAGIS, Julien HANSON, Patrick SEGERS, P GERARD, Bernard MASEREEL, Vincent D'ORIO, Raymond LIMET
2005
Pharmacological profile and therapeutic potential of BM-573, a combined thromboxane receptor antagonist and synthase inhibitor, in Cardiovascular Drug Reviews, volume 23, pp. 1-14
Alexandre GHUYSEN, Jean-Michel DOGNÉ, Patrice CHIAP, Stéphanie ROLIN, Bernard MASEREEL, Bernard LAMBERMONT, Philippe KOHL, Vincent TCHANA-SATO, Julien HANSON, Vincent DORIO
2005
In vitro and in vivo pharmacological characterization of BM-613, a novel dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in Journal of Pharmacology and Experimental Therapeutics, volume 313, issue 1, pp. 293-301
Julien HANSON, Stéphanie ROLIN, D REYNAUD, N QIAO, L KELLEY, H REID, F VALENTIN, J TIPPINS, T KINSELLA, Bernard MASEREEL, C PACE-ASCIAK, Bernard PIROTTE, Jean-Michel DOGNÉ
2005
Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig, in Thrombosis Research, volume 116, issue 5, pp. 431-442
Jean-Michel DOGNÉ, Marie-Pierre ROLIN, Michel PETEIN, Vincent TCHANA-SATO, Alexandre GHUYSEN, Bernard LAMBERMONT, Julien HANSON, David MAGIS, Patrick SEGERS, Bernard PIROTTE, Bernard MASEREEL, Pierre DRION, Vincent D'ORIO, Philippe KOLH
2004
2004
Effect of a novel thromboxane A2 inhibitor on right ventricular-arterial coupling in endotoxic shock, in Shock, volume 21, issue 1, pp. 45-51
Bernard LAMBERMONT, Philippe KOHL, Alexandre GHUYSEN, Patrick SEGHERS, Jean-Michel DOGNÉ, Vincent TCHAN-SATO, Philippe MORIMONT, Patricia BENOIT, P GERARD, Bernard MASEREEL, Vincent D'ORIO
2004
New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators, in Current Medicinal Chemistry, volume 11, issue 10, pp. 1223-1241
Jean-Michel DOGNÉ, Xavier DE LEVAL, Julien HANSON, Michel FREDERICH, Bernard LAMBERMONT, Alexandre GHUYSEN, Angela CASINI, Bernard MASEREEL, KH RUAN, Bernard PIROTTE, Philippe KOLH
2004
Carbonic anhydrase inhibitors - Design of anticonvulsant sulfonamides incorporating indane moieties, in Bioorganic and Medicinal Chemistry Letters, volume 14, pp. 5781-5786
Celine CHAZALETTE, Bernard MASEREEL, Stéphanie ROLIN, Anne THIRY, Andrea SCOZZAFAVA, Alessio INNOCENTI, Claudiu T. SUPURAN
2004
New developments on thromboxane modulators, in Mini-Reviews in Medecinal Chemistry, volume 4, pp. 649-657
Jean-Michel DOGNÉ, Julien HANSON, Xavier DE LEVAL, Bernard MASEREEL, Philippe KOHL, Bernard PIROTTE
2003
Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II): effects of BM-567 on platelet function, in Prostaglandins Leukotrienes and Essential Fatty Acids, volume 68, pp. 49-54
Jean-Michel DOGNÉ, Xavier DE LEVAL, Philippe KOHL, V. SANNA, Stéphanie ROLIN, Catherine MICHAUX, M. MAUER, Jean-Louis DAVID, Bernard MASEREEL, Bernard PIROTTE
2003
Effects of endotoxic shock on right ventricular systolic function and mechanical efficiency, in Cardiovascular Research, volume 59, pp. 412-418
Bernard LAMBERMONT, A GHUYSEN, Philippe KOLH, Vincent TCHANA-SATO, P SEGERS, P GÉRARD, Philippe MORIMONT, D MAGIS, Jean-Michel DOGNÉ, Bernard MASEREEL, Vincent D'ORIO
2003
Pharmacological evaluation of the novel thromboxane modulator BM-567 (II/II). Effects of BM-567 on osteogenic sarcoma-cell-induced platelet aggregation, in Prostaglandins Leukotrienes and Essential Fatty Acids, volume 68, pp. 55-59
Xavier DE LEVAL, Valérie BENOIT, Jacques DELARGE, Fabien JULÉMONT, Bernard MASEREEL, Benard PIROTTE, Marie-Paule MERVILLE, Jean-Louis DAVID, Jean-Michel DOGNÉ
2003
Effects of U-46619 on pulmonary hemodynamics before and after administration of BM-573, a novel thromboxane A2 inhibitor, in Arch Physiol Biochem, volume 111, issue 3, pp. 217-223
Bernard LAMBERMONT, Phillipe KOHL, Jean-Michel DOGNÉ, Alexandre GHUYSEN, Vincent TCHANA-SATO, Philippe MORIMONT, Patricia BENOIT, P GÉRARD, Bernard MASEREEL, Raymond LIMET, Vincent D'ORIO
2003
3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo, in British Journal of Cancer, volume 88, pp. 1111-1118
Isabelle KEMPEN, D PAPAPOSTOLOU, Nicole THIERRY, Lionel POCHET, Stéphane COUNEROTTE, Bernard MASEREEL, Jean-Michel FOIDART, Michèle REBOUD-RAVAUX, Agnès NOEL, Bernard PIROTTE
2003
BM-573, a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist Prevents Pig Myocardial Infarction Induced by Coronary Thrombosis, in Journal of Pharmacology and Experimental Therapeutics, volume 306, pp. 59-65
Stéphanie ROLIN, Michel PETEIN, Vincent TCHANA-SATO, Jean-Michel DOGNÉ, Patricia BENOIT, Bernard LAMBERMONT, Alexandre GHUYSEN, Philippe KOHL, Bernard MASEREEL
2003
Investigation of the inhibition mechanism of coumarins on chymotrypsin by mass spectrometry, in Tetrahedron, volume 59, pp. 4557-4561
Lionel POCHET, Marc DIEU, Raphael FRÉDÉRICK, Anne-Marie MURRAY, Isabelle KEMPEN, Bernard PIROTTE, Bernard MASEREEL
2002
Synthesis and biological evaluation of aroylguanidines related to amiloride as inhibitors of the human platelet Na+/H+ exchanger, in Bioorganic & Medicinal Chemistry, volume 10, issue 6, pp. 1793-1804
Didier LAECKMANN, Françoise ROGISTER, Jean-Victor DEJARDIN, Christelle PROSPERI-MEYS, Joseph GÉCZY, Jacques DELARGE, Bernard MASEREEL
2002
Therapeutic potential of thromboxane inhibitors in asthma, in Expert Opinion on Investigational Drugs, volume 11, pp. 1-8
Jean-Michel DOGNÉ , Xavier DE LEVAL, Patricia BENOIT, Stéphanie ROLIN, Bernard PIROTTE, Bernard MASEREEL
2002
Thromboxane A2 inhibition : Therapeutic potential in bronchial asthma., in American Journal of Respiratory Medicine, volume 1, pp. 11-17
Jean-Michel DOGNÉ, Xavier DE LEVAL, Patricia BENOÎT, Jacques DELARGE, Bernard MASEREEL
2002
Recent advances in antiplatelet agents, in Current Medicinal Chemistry, volume 9, pp. 577-589
Jean-Michel DOGNÉ, Xavier DE LEVAL, P BENOÎT, Jacques DELARGE, Bernard MASEREEL, Jean-Louis DAVID
2002
In vitro and in vivo effects of new insulin releasing agents, in Biochemical Pharmacology, volume 63, issue 3, pp. 515-521
Quynh-Anh NGUYEN, Marie-Hélène ANTOINE, Raogo OUEDRAOGO, Marcel HERMANN, Jacqueline SERGOORIS, Bernard PIROTTE, Bernard MASEREEL, Philippe LEBRUN
2001
Evaluation of classical NSAIDs and COX-2 selective inhibitors on purified ovine enzymes and human whole blood, in Prostaglandins Leukotrienes and Essential Fatty Acids, volume 64, pp. 211-216
Xavier DE LEVAL, Jacques DELARGE, Philippe DEVEL, Phillipe NEVEN, Catherine MICHAUX, Bernard MASEREEL, Bernard PIROTTE, Jean-Louis DAVID, Yves HENROTIN, Jean-Michel DOGNÉ
2001
Pharmacology of the thromboxane receptor antagonist and thromboxane synthase inhibitor BM-531, in Cardiovascular Drug Reviews, volume 19, pp. 87-96
Jean-Michel DOGNÉ, Stéphanie ROLIN, Xavier DE LEVAL, Phillipe NEVEN, Jacques DELARGE, Philippe KOLH, Jacques DAMAS, Jean-Louis DAVID, Bernard MASEREEL
2001
Design, synthesis and biological evaluation of a sulfonylcyanoguanidine as thromboxane A2 receptor antagonist and thromboxane synthase inhibitor, in Journal of Pharmacy and Pharmacology, issue 53, pp. 669-680
Jean-Michel DOGNÉ, Johan WOUTERS, Stéphanie ROLIN, Catherine MICHAUX, Lionel POCHET, François DURANT, Jacques DELARGE, Bernard MASEREEL
2001
2001
Novel inhibitors of sodium-calcium exchanger: benzene ring analogues of N-guanidino substituted amiloride derivatives., in European Journal of Medicinal Chemistry, volume 36, pp. 597-614
Françoise ROGISTER, Didier LAECKMANN, PO PLASMAN, F VAN EYLEN, M GHYOOT, C MAGGETTO, Jean-François LIÉGEOIS, Jozef GECZY, André HERCHUELZ, Jacques DELARGE, Bernard MASEREEL
2000
Pharmacomodulation studies of torasemide led to original non-carboxylic thromboxane A2 receptor antagonists, in Pharmacy and Pharmacology Communication, volume 6, pp. 77-82
Jean-Michel DOGNÉ, Xavier DE LEVAL, Philippe NEVEN, Stéphanie ROLIN, Fabian SOMERS, Johan WOUTERS, Jacques DELARGE, Bernard MASEREEL
2000
Coumarinic derivatives as mechanism-based inhibitors of &-chymotrypsin and human leukocyte elastase, in Bioorganic and Medicinal Chemistry, issue 8, pp. 1489-1501
Lionel POCHET, Caroline DOUCET, Georges DIVE, Johan WOUTERS, Bernard MASEREEL, Michèle REBOUD-RAVAUX, Bernard PIROTTE
2000
Isosterism among analogues of torasemide: conformational, electronic and lipophilic properties, in European Journal of Medicinal Chemistry, volume 35, pp. 923-929
Johan WOUTERS, Catherine MICHAUX, François DURANT, Jean Michel DOGNÉ, Jacques DELARGE, Bernard MASEREEL
2000
New Trends in Thromboxane and Prostacyclin Modulators, in Current Medicinal Chemistry , volume 7, pp. 609-628
Jean-Michel DOGNÉ, Xavier DE LEVAL, Jacques DELARGE, Jean-Louis DAVID, Bernard MASEREEL
2000
2000
Effects of a novel non-carboxylic thromboxane A2 receptor antagonist (BM-531) derived from torasemide on platelet function, in Prostaglandins Leukotrienes and Essential Fatty Acids, volume 62, pp. 311-317
Jean-Michel DOGNÉ, Xavier DE LEVAL, Philippe NEVEN, Stéphanie ROLIN, Johan WOUTERS, Jean-Louis DAVID, Jacques DELARGE, Bernard MASEREEL
2000
Comparison of the effects of nimesulide and nimesulide-L-lysine on PGE2 production by COX-1 and COX-2 and on chondrocyte metabolism in-vitro, in Pharmacy and Pharmacology Communication, volume 6, pp. 83-87
Xavier DE LEVAL, Yves HENROTIN, A LABASSE, Jean-Yves REGINSTER, Philippe NEVEN, Jacques DELARGE, Fabian SOMERS, Bernard MASEREEL, Bernard PIROTTE, Jean-Michel DOGNÉ
1999
Thromboxane A2 receptor antagonism in man and rat by a sulphonylcyanoguanidine (BM-144) and a sulphonylurea (BM-500), in Journal of Pharmacy and Pharmacology, volume 51, pp. 695-701
Bernard MASEREEL, Jacques DAMAS, Jeanine FONTAINE, Martine LEMBÈGE, Fabrice LACAN, Alain NUHRICH, Jacques DELARGE, Lionel POCHET, Jean-Michel DOGNÉ
1999
Insulinotropic effect of new glibenclamide isosteres, in Journal of Pharmacology and Experimental Therapeutics, volume 289, pp. 625-631
R OUEDRAOGO, QA NGUYEN, Marie-Hélène ANTOINE, C KANE, MJ DUNNE, Lionel POCHET, Bernard MASEREEL, Philippe LEBRUN
1998
Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives, in Journal of Medecinal Chemistry, volume 41, pp. 1138-1145
H UCAR, K VAN DERPOORTEN , S CACCIAGUERRA, S SPAMPINATO, S STABLES, Paul DEPOVERE, M ISA, Bernard MASEREEL, Jacques DELARGE, Jacques POUPAERT
1998
Pyridothiadiazinedioxides structurally related to quinazolinones cholecystokinin/gastrin receptor ligands : synthesis and biological evaluation, in European Journal of Pharmaceutical Sciences, volume 7, pp. 29-40
Bernard PIROTTE, Pascal DE TULLIO, Tchao PODONA, Ousman DIOUF, Daniel DEWALQUE, Philippe NEVEN, Bernard MASEREEL, Daniel Henri CAIGNARD, Pierre RENARD, Jacques DELARGE
1997
Anticonvulsant activity of pyrid-3-yl-sulfonyl urea and thiourea., in Epilepsia, volume 38, pp. 334-337
Bernard MASEREEL, Didier LAMBERT, Jean-Michel DOGNÉ, Jacques POUPAERT, Jacques DELARGE
1997
Synthesis and Biological Evaluation of Sulfonylcyanoguanidines and Sulfonamidonitroethylenes as Bioisosteres of Hypoglycemic sulfonylureas., in European Journal of Medicinal Chemistry, volume 32, pp. 453-456
Bernard MASEREEL, R OUEDRAOGO, Jean-Michel DOGNÉ, Marie-Hélène ANTOINE, Pascal DE TULLIO, Bernard PIROTTE, Lionel POCHET, Jacques DELARGE, Philippe LEBRUN

Conference Proceedings

2011
Indole-pyridinyl-ethanones as novel inhibitors of indoleamine-2,3- dioxygenase (IDO), a promising target for anti-cancer immunotherapy, in Book of Abstracts, 47èmes RICT, 6-8 juillet 2011, Lyon, France, volume IS08, pp. 136-136
Eduard DOLUSIC, Pierre LARRIEU, Sébastien BLANC, Laurence MOINEAUX, Frédéric SAPUNARIC, Jenny POUYEZ, Delphine COLETTE, Graeme FRASER, Vincent STROOBANT, Luc PILOTTE, Didier COLAU, Jean-Marie FRÈRE, Bernard MASEREEL, Benoît VAN DEN EYNDE, Johan WOUTERS, Raphael FRÉDÉRICK
2011
Novel Inhibitors of Indoleamine 2,3-Dioxygenase (IDO), a Target for Anti-Cancer Immunotherapy, in Book of Abstracts, XVIIIème Journée Jeunes Chercheurs, 04/02/11, Paris, France
Eduard DOLUSIC, Sébastien BLANC, Pierre LARRIEU, Laurence MOINEAUX, Delphine COLETTE, Graeme FRASER, Vincent STROOBANT, Luc PILOTTE, Didier COLAU, Johan WOUTERS, Bernard MASEREEL, Benoît VAN DEN EYNDE, Raphael FRÉDÉRICK
2011
Indole-pyridinyl-ethanones as novel inhibitors of indoleamine-2,3-dioxygenase (IDO), a promising target for anti-cancer immunotherapy, in Book of Abstracts, 25èmes Journées Franco-belges de Pharmacochimie, 19-20/05/11, Liège, volume P37, pp. 62-62
Eduard DOLUSIC, Pierre LARRIEU, Sébastien BLANC, Laurence MOINEAUX, Delphine COLETTE, Graeme FRASER, Vincent STROOBANT, Luc PILOTTE, Didier COLAUX, Johan WOUTERS, Bernard MASEREEL, Benoît VAN DEN EYNDE, Raphael FRÉDÉRICK
2011
Synthesis, structural, enzymatic and cellular studies of vinyl-1H-indole analogues as potential inhibitors of tryptophan 2,3-dioxygenase (TDO), an attractive target in cancer immunotherapy., in Book of Abstracts, Emerging Targets and Treatments: Opportunities and Challenges for Drug Design, Ghent, 25 November 2011, volume P22
Laurence MOINEAUX, Caroline CHARLIER, Eduard DOLUSIC, Pierre LARRIEU, Luc PILOTTE, Didier COLAU, Vincent STROOBANT, Paulette CHARLIER, Sophie LAURENT, Moreno GALLENI, Bernard MASEREEL, Benoît VAN DEN EYNDE, Johan WOUTERS, Raphael FRÉDÉRICK
2011
LECTURE: Indoleamine 2,3-Dioxygenase Inhibitory Activity of Derivatives of Marine Alkaloid Tsitsikammamine A, in Book of Abstracts, 25èmes Journées Franco-belges de Pharmacochimie, 19-20/05/11, Liège, volume OC10, pp. 22-22
Eduard DOLUSIC, Pierre LARRIEU, Delphine COLETTE, Sébastien BLANC, Arnaud RIVES, Graeme FRASER, Johan WOUTERS, Robert KISS, Benoît VAN DEN EYNDE, Bernard MASEREEL, Evelyne DELFOURNE, Raphael FRÉDÉRICK
2011
THIOSEMICARBAZONES AS INHIBITORS OF TRYPTOPHAN 2,3-DIOXYGENASE (TDO), AN EMERGING TARGET FOR CANCER TREATMENT, in Book of Abstracts, Emerging Targets and Treatments: Opportunities and Challenges for Drug Design, Ghent, 25 November 2011, volume P21
Eduard DOLUSIC, Sara MODAFFARI, Pierre LARRIEU, Christelle VANCRAEYNEST, Luc PILOTTE, Didier COLAU, Vincent STROOBANT, Benoît VAN DEN EYNDE, Johan WOUTERS, Bernard MASEREEL, Raphael FRÉDÉRICK
2011
Discovery and preliminary SARs of new scaffolds of tryptophan 2,3-dioxygenase (TDO) inhibitors using virtual screening, in Book of Abstracts, 25èmes Journées Franco-belges de Pharmacochimie, 19-20/05/11, Liège, volume P19, pp. 44-44
Laurence MOINEAUX, Caroline CHARLIER, Eduard DOLUSIC, Pierre LARRIEU, Luc PILOTTE, Didier COLAU, Vincent STROOBANT, Moreno GALLENI, Bernard MASEREEL, Benoît VAN DEN EYNDE, Johan WOUTERS, Raphael FRÉDÉRICK
2011
SYNTHESIS, ACTIVITY, CRYSTAL AND ELECTRONIC PROPERTIES OF ISOMERS OF CHLORO-PYRIDINYLVINYL-1H-INDOLES, in Book of Abstracts, 25èmes Journées Franco-belges de Pharmacochimie, 19-20/05/11, Liège, volume P20, pp. 45-45
Laurence MOINEAUX, Sophie LAURENT, Eduard DOLUSIC, Jérémy RENIERS, Bernadette NORBERG, Jean-Marie FRÈRE, Moreno GALLENI, Benoît VAN DEN EYNDE, Bernard MASEREEL, Raphael FRÉDÉRICK, Johan WOUTERS
2011
2010
Introduction to microparticles: 2010 and future, in Sta user's meeting, Paris
François MULLIER, Nicolas BAILLY, Jean-Michel DOGNÉ, Bernard CHATELAIN
2010
Tryptophan 2,3-dioxygenase (TDO) inhibitors : Identification of new scaffolds using virtual screening, in Abstracts, Journée scientifique de la Société royale de chimie (SRC), Gembloux, Belgium, 14 October 2010
Laurence MOINEAUX, Caroline CHARLIER, Eduard DOLUSIC, Pierre LARRIEU, Luc PILOTTE, Didier COLAU, Vincent STROOBANT, Moreno GALLENI, Bernard MASEREEL, Benoît VAN DEN EYNDE, Johan WOUTERS, Raphael FRÉDÉRICK
2010
Microparticle Generation Assay: a new tool to diagnose and study the physiopathology of type-II HIT, in 56th Annual Scientific and StandardizationCommittee Meeting (SSC) of the International Society of Thrombosis and Hemostasis (ISTH), Cairo
François MULLIER, Nicolas BAILLY, Yvan CORNET, Eric DUBUC, Séverine ROBERT, Jean-Claude OSSELAER, Christian CHATELAIN, Ismail ELALAMY, Jean-Michel DOGNÉ, Bernard CHATELAIN
2010
Conception, synthèse et étude d'inhibiteurs de la tryptophane 2,3-dioxygénase (TDO), une cible prometteuse pour le traitement du cancer, in Abstracts, Séminaire des jeunes chercheurs Télévie 2011, Brussels, Belgium, 7 December 2010
Laurence MOINEAUX, Caroline CHARLIER, Eduard DOLUSIC, Pierre LARRIEU, Luc PILOTTE, Didier COLAU, Vincent STROOBANT, Moreno GALLENI, Bernard MASEREEL, Benoît VAN DEN EYNDE, Johan WOUTERS, Raphael FRÉDÉRICK
2010
SYSTEMIC IMMUNE RESPONSE DURING THE EARLY PHASE OF WOUND HEALING AFTER SINUS SURGERY, in Belgian Rhinology Society 2010
Jean-Baptiste WATELET, François MULLIER, Yvan CORNET, Philippe ELOY, Youri GLUPCZYNSKI, Bernard CHATELAIN
2010
Platelet Microparticle Generation Assay: a valuable and simpler alternative to 14C-SRA for type-II HIT diagnosis: selection for oral presentation, in European Society for Clinical Cell Analysis, Valencia, September 2010
François MULLIER, Nicolas BAILLY, Yvan CORNET, Eric DUBUC, Séverine ROBERT, Jean-Claude OSSELAER, Christian CHATELAIN, Ismail ELALAMY, Jean-Michel DOGNÉ, Bernard CHATELAIN
2010
Synthesis, crystal and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles, in Abstracts, The sixth Belgian Crystallography Symposium (BCS-6), 13 October 2010, Brussels, Belgium
Laurence MOINEAUX, Caroline CHARLIER, Eduard DOLUSIC, Pierre LARRIEU, Luc PILOTTE, Didier COLAU, Vincent STROOBANT, Moreno GALLENI, Bernard MASEREEL, Benoît VAN DEN EYNDE, Johan WOUTERS, Raphael FRÉDÉRICK
2010
Study of small particles by flow cytometry: Present and future, in Abstract Book International Society for Analytical Cytology (ISAC 2010), Seattle
François MULLIER, Jean-Michel DOGNÉ, Nicolas BAILLY, Yvan CORNET, Severine ROBERT, Bernard CHATELAIN
2010
Design, synthesis and study of inhibitors of tryptophan 2,3-dioxygenase (TDO), a promising target for cancer therapy, in Abstracts, école doctorale Structure et Fonction des Macromolécules Biologiques, Bioinformatique et Modélisation (SFMBBM), Liège, Belgium, 10 December 2010
Laurence MOINEAUX, Caroline CHARLIER, Eduard DOLUSIC, Pierre LARRIEU, Luc PILOTTE, Didier COLAU, Vincent STROOBANT, Moreno GALLENI, Bernard MASEREEL, Benoît VAN DEN EYNDE, Raphael FRÉDÉRICK
2010
Indole-pyridinyl-ethanones as Novel Inhibitors of Indoleamine 2,3-Dioxygenase (IDO), a Promising Target for Anti-Cancer Immunotherapy, in Book of Abstracts, XXIVth European Colloquium on Heterocyclic Chemistry, Vienna, Austria, August 23-27, 2010, pp. PO-41
Eduard DOLUSIC, Sébastien BLANC, Pierre LARRIEU, Laurence MOINEAUX, Delphine COLETTE, Graeme FRASER, Vincent STROOBANT, Luc PILOTTE, Didier COLAU, Johan WOUTERS, Bernard MASEREEL, Benoît VAN DEN EYNDE, Raphael FRÉDÉRICK
2009
Contribution of Platelet Microparticles Generation Assay to the Diagnosis of Type II Heparin-induced Thrombocytopenia., in Abstract Book - Annual Meeting of Belgian Society on Thrombosis and Haemostasis
François MULLIER, Nicolas BAILLY, Yvan CORNET, Eric DUBUC, Severine ROBERT, Jean-Claude OSSELAER, Christian CHATELAIN, Bernard CHATELAIN
2009
Effects of leaf extracts from Croton zambesicus on hemostasis., in Abstract book - 23èmes Journées Franco-Belges de Pharmacochimie
Severine ROBERT, Chiara BACCELLI, Philippe DEVEL, Jean-Michel DOGNÉ, Joëlle QUETIN-LECLERCQ
2009
Interest of mepacrine testing in the storage-pool disease, in ESCCA 2009 Saint-Etienne France
François MULLIER, Véronique LATGER-CANNARD, Yvan CORNET, Bailly BAILLY, Bernard CHATELAIN
2009
Cytologie des syndromes myélodysplasiques avec ider(20q)., in Groupe Français d'Hématologie Cellulaire (GFHC) 2009 Bruxelles
François MULLIER, Sylvie DALIPHARD, Richard GARAND, Mélanie DEKEYSER, Yvan CORNET, Isabelle LUQUET, Pascaline TALMANT, Steven RICHEBOURG, Mauricette JAMAR, Jean-Michel DOGNÉ, Christian CHATELAIN, Lucienne MICHAUX, Bernard CHATELAIN
2009
2009
Platelets and microparticles, in Molecular Biology and Cytometry Course, ABCA/BVAC 2009
François MULLIER, Jean-Michel DOGNÉ, Bernard CHATELAIN
2009
2008
Nanotoxico: Toxicological assessment of engineered nanoparticles using in vitro and in vivo models.
Stéphanie ROLIN, Bernard MASEREEL, Sebastien VANKONINGSLOO, Jean-Pascal PIRET, Stephane LUCAS, Olivier TOUSSAINT
2008
High-speed cell sorting, in BD sorter User's meeting 2008
François MULLIER, Nicolas BAILLY, Jean-Michel DOGNÉ, Bernard CHATELAIN
2008
Contribution of platelet microparticles assay to type II HIT, in Abstract Book-Association Belge de Cytologie Analytique 2008 (ABCA/BVAC)
François MULLIER, Nicolas BAILLY, Yvan CORNET, Severine ROBERT, Jean-Michel DOGNÉ, Bernard CHATELAIN
2008
Résultats d'une étude tricentrique sur le système INR : Intérêt d'un kit de contrôle et de calibration, in Abstract Book-Groupe Etude Hemostase Thrombose 2008
Hassan MEKOUAR, François MULLIER, Yvan CORNET, Eric DUBUC, Marc CHATELAIN, Mélanie DEKEYSER, Patrick VANDEKERKOVE, Bernard CHATELAIN
2007
Thrombin activity profile: a rapid, reliable and relevant ex vivo screening test for the development of anticoagulant drugs, in Abstract Book-13th Belgian Forum of Pharmaceutical Sciences
Severine ROBERT, Jérémie GHIOTTO, Bernard PIROTTE, Jean-Louis DAVID, Bernard MASEREEL, Lionel POCHET, Jean-Michel DOGNÉ
2007
Inhibiteurs d'anhydrases carboniques. Evaluation de l'effet anticonvulsivant d'indanesulfonamides, in Abstract Book-21èmes Journées Franco-Belges de Pharmacochimie
Anne THIRY, Aurélie FRANKART, Catherine MICHAUX, Jean-Michel DOGNÉ, Claudiu T. SUPURAN, Johan WOUTERS, Bernard MASEREEL
2007
Le profil d'activité de thrombine: un puissant test de criblage ex vivo pour le développement d'agents anticoagulants, in Abstract Book-21èmes Journées Franco-Belges de Pharmacochimie
Severine ROBERT, Jérémie GHIOTTO, Bernard PIROTTE, Jean-Louis DAVID, Bernard MASEREEL, Lionel POCHET, Jean-Michel DOGNÉ
2007
2006
The use of an apoE-deficient (apoE-/-) mice model to charaterize the therapeutic benefits of original thromboxane modulators. , in Abstract book - Bioforum, pp. 123
Céline CHERDON, Stéphanie ROLIN, Julien HANSON, Laurence DE LEVAL, Pierre-Vincent DRION, Joel PINCEMAIL, Jean-Michel DOGNÉ, Jean-Olivier DEFRAIGNE
2005
Structure-based design of coumarins as potent thrombin inhibitors, in Abstract Book-19èmes Journées Franco-Belges de Pharmacochimie
Raphael FRÉDÉRICK, Severine ROBERT, Caroline CHARLIER, Jerome DE RUYCK, Bernard MASEREEL, Lionel POCHET
2005
Developpement d'indanesulfonamides inhibiteurs de l'anhydrase carbonique IX, in Abstract Book-19èmes Journées Franco-Belge de pharmacochimie
Anne THIRY, Marie LEDECQ, Celine CHAZALETTE, Johan WOUTERS, Claudiu T. SUPURAN, Bernard MASEREEL
2004
Coumarins as serine protease inhibitors, in Abstract Book-XVIIIth International Symposium on Medicinal Chemistry
Lionel POCHET, Raphael FRÉDÉRICK, Severine ROBERT, Stéphanie ROLIN, Bernard MASEREEL
2004
2004
Étude du mode d'interaction de coumarines avec la thrombine, in Abstract Book-18èmes Journées Franco-Belges de Pharmacochimie
Raphael FRÉDÉRICK, Caroline CHARLIER, Jerome DE RUYCK, Marc DIEU, Severine ROBERT, Bernard MASEREEL, Lionel POCHET
2003
Synthèse de beta-cyclodextrines modifiées, in Abstract Book-17èmes Journées Franco-Belges de Pharmacochimie
Carine BERTOLLA, Marie PIETTE, Brigitte EVRARD, Luc DELATTRE, Géraldine PIEL, Raphael FRÉDÉRICK, Bernard MASEREEL
2001
Synthèse et évaluation pharmacologique d'un méthanesulfonamide pyridinique apparenté à l'acide niflumique, in Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie, pp. 49
Fabien JULÉMONT, Xavier DE LEVAL, Philippe NEVEN, Philippe DEVEL, Bernard PIROTTE, Jacques DELARGE, Bernard MASEREEL, Catherine MICHAUX, Jean-Michel DOGNÉ
2001
Comparaison de l'effet de deux dérivés de l'acide 6-(acétoxyméthyl)-2-oxo-2H-1-benzopyrane-3-carboxylique sur l'inhibition de l'invasion cellulaire in vitro et in vivo, in Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie, pp. 73
Isabelle KEMPEN, Serge POCHET, D PAPAPOSTOLOU, Stéphane COUNEROTTE, Bernard MASEREEL, Jean-Michel FOIDART, Michèle REBOUD-RAVAUX, Francis FRANKENNE, Bernard PIROTTE
2001
Towards new leads for selective cyclooxygenase-2 (COX-2) inhibition, in Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie, pp. 84
Catherine MICHAUX, Stéphanie ROLIN, Xavier DE LEVAL, Bernard MASEREEL, François DURANT, Johan WOUTERS
2001
Effects of thromboxane A2 receptor antagonists and COX inhibitors on osteogenic sarcoma cell-induced platelet aggregation, in Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie., pp. 69
Xavier DE LEVAL, Jacques DELARGE, Philippe NEVEN, Catherine MICHAUX, Bernard MASEREEL, Bernard PIROTTE, Jean-Louis DAVID, Jean-Michel DOGNÉ
2001
In vitro biological evaluation of two cyclooxygenase-2 inhibitors, in Abstract book - XIVèmes Journées franco-belges de pharmacochimie
Stéphanie ROLIN, Carine MICHIELS, Bernard MASEREEL, Xavier DE LEVAL, François DURANT, Catherine MICHAUX
2001
Antiplatelet and antithrombotic properties of BM-573, a novel combined thromboxane receptor antagonist and thromboxane synthase inhibitor, in Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie, pp. 70
Jean-Michel DOGNÉ, Patricia BENOIT, Xavier DE LEVAL, Philippe NEVEN, Stéphanie ROLIN, Catherine MICHAUX, Jean-Louis DAVID, Jacques DELARGE, Bernard MASEREEL
1999

Scientific reviews

2010
Quantification du fibrinogène par électrophorèse capillaire, in Groupe Etude Hémostase Thrombose, Dijon, October 22-23th; 2010
Massin LEBITASY, François MULLIER, Hassan MEKOUAR, Diane MAISIN, Bernard CHATELAIN, Dominique LATINNE, Stéphane EECKHOUDT
2010
2010
The tick protein Ir-CPI efficiently delays contact pathway induced thrombin generation and displays in vivo antithrombotic activity, in 49) NARILIS symposium. Faculté de Médecine. FUNDP Namur. October 23th, 2010
Severine ROBERT, Yves DECREM, Géraldine RATH, Chantal DESSY, Olivier FERON, François MULLIER, Philippe DEVEL, Bernard CHATELAIN, Jean-Michel DOGNÉ, Edmond GODFROID
2010
The calibrated thrombin generation test (cTGT) : a gold standard assay to assess the procoagulant activity of nanomaterials, in 50) NARILIS symposium. Faculté de Médecine. FUNDP Namur. October 23th, 2010
Julie LALOY, Severine ROBERT, Catherine MARBEHANT, François MULLIER, Jorge Humberto MEJIA MENDOZA, Jean-Pascal PIRET, Joseph DELHALLE, Stephane LUCAS, Bernard CHATELAIN, Jean-Michel DOGNÉ, Olivier TOUSSAINT, Bernard MASEREEL, Stéphanie ROLIN
2010
STRUCTURAL AND ENZYMATIC STUDY OF TRYPTOPHAN 2,3- DIOXYGENASE (TDO), A POTENTIAL TARGET IN ANTICANCER IMMUNOTHERAPY, in Drugs of the Future, volume 35, issue suppl. A, pp. 217-218
Laurence MOINEAUX, Caroline CHARLIER, Eduard DOLUSIC, Pierre LARRIEU, Luc PILOTTE, Didier COLAU, Vincent STROOBANT, Moreno GALLENI, Bernard MASEREEL, Benoît VAN DEN EYNDE, Johan WOUTERS, Raphael FRÉDÉRICK
2010
Implication of tissue-factor bearing microparticles in thrombosis associated with breast cancer , in European Society for Clinical Cell Analysis, Valencia, September 2010
François MULLIER, Damien GHELDOF, Séverine ROBERT, Nicolas BAILLY, Philippe DEVEL, Bernard CHATELAIN, Jean-Michel DOGNÉ
2010
2010
Comparaison de la vitesse de sédimentation de deux automates par rapport à la méthode de Westergren, in Corata, Marseille September 2010:
Hassan MEKOUAR, Catherine ROLIN, Javier HERNANDEZ, Yvan CORNET, François MULLIER, Bernard CHATELAIN
2010
Discovery and Optimization Of Indole-pyridinyl-ethanones as Novel Inhibitors of Indoleamine-2,3-Dioxygenase (IDO), a Promising Target for Anti-Cancer Immunotherapy, in Drugs of the Future, volume 35, issue suppl. A, pp. 181-182
Raphael FRÉDÉRICK, Sébastien BLANC, Pierre LARRIEU, Laurence MOINEAUX, Delphine COLETTE, Graeme FRASER, Vincent STROOBANT, Luc PILOTTE, Didier COLAU, Johan WOUTERS, Bernard MASEREEL, Benoît VAN DEN EYNDE, Eduard DOLUSIC
2010
Implication of tissue-factor bearing microparticles in thrombosis associated with breast cancer , in Belgian Society of Clinical Biology, Anvers, October 16th; 2010
François MULLIER, Damien GHELDOF, Severine ROBERT, Nicolas BAILLY, Philippe DEVEL, Carine MICHIELS, Chantal DOYEN, Chatelain CHRISTIAN, Bernard CHATELAIN, Jean-Michel DOGNÉ
2010
Platelet Microparticle Generation Assay: a valuable and simpler alternative to 14C-SRA for type-II HIT diagnosis., in Belgian Society of Clinical Biology, Anvers, October 16th; 2010
François MULLIER, Nicolas BAILLY, Yvan CORNET, Severine ROBERT, Jean-Claude OSSELAER, Christian CHATELAIN, Ismail ELALAMY, Jean-Michel DOGNÉ, Bernard CHATELAIN
2009
A novel concept to improve diagnosis of Hereditary Spherocytosis., in Abstract Book-Société Belge Biologie Clinique 2009
François MULLIER, Nicolas BAILLY, Yvan CORNET, Jean-Michel DOGNÉ, Bernard CHATELAIN
2009
Accurate quantification of microparticles by flow cytometry: important issues. , in Journal of Thrombosis and Haemostasis, volume 7, issue 2, pp. 329
François MULLIER, Jean-Michel DOGNÉ, Nicolas BAILLY, Yvan CORNET, Severine ROBERT, Bernard CHATELAIN
2009
Synthesis, molecular modeling and pharmacological evaluation of pyrazoloisoquinolines as potential anti-polyarthritis drugs
Jérémie MORTIER, Corinne GANEFF, Caroline REMOUCHAMPS, Emmanuel DEJARDIN, Patrice TALAGA, Jacques PIETTE
2009
Potential nanotoxicity in blood : Effects of engineered nanoparticles on human blood constituents, in Nanofac 2009
Julie LALOY, Catherine MARBEHANT, Severine ROBERT, François MULLIER, Bernard CHATELAIN, Jean-Michel DOGNÉ, Olivier TOUSSAINT, Bernard MASEREEL, Stéphanie ROLIN
2009
Pyrazolo(4,3-c)isoquinolines as potential inhibitors of NF-kB activation
Jérémie MORTIER, Raphaël FREDERICK, Corinne GANEFF, Caroline REMOUCHAMPS, Patrice TALAGA, Jacques PIETTE, Bernard MASEREEL
2008
rt-PCR in diagnosis of alpha-thalassemia : a future alternative?, in Abstract Book-Brussels 2008
Hassan MEKOUAR, François MULLIER, Caroline DEBECKER, Marianne PHILIPPE
2008
Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors, in Drugs of the Future, volume 33, issue suppl A, pp. 266
Severine ROBERT, Carine BERTOLLA, Bernard MASEREEL, Jean-Michel DOGNÉ, Lionel POCHET
2008
Structural insights into the inhibition mode of the activated coagulation factor XII by coumarins, in Drugs of the Future, volume 33, issue suppl A, pp. 267
Catherine MICHAUX, Severine ROBERT, Marie DEL TEDESCO, Bernard MASEREEL, Jean-Michel DOGNÉ, Lionel POCHET
2007
Thrombin activity profile: a powerful ex vivo screening test for the development of anticoagulant drugs, in Journal of Thrombosis and Haemostasis, volume 5, issue Suppl. 2, pp. PW-073
Severine ROBERT, Jérémie GHIOTTO, Bernard PIROTTE, Jean-Louis DAVID, Bernard MASEREEL, Lionel POCHET, Jean-Michel DOGNÉ
2006
Design, synthesis and biological evaluation of indanesulfonamides as carbonic anhydrase IX inhibitors, in Fundamental and Clinical Pharmacology, volume 20, pp. 626
Anne THIRY, Marie LEDECQ, Alessandro CECCHI, Jean-Michel DOGNÉ, Johan WOUTERS, Claudiu T. SUPURAN, Bernard MASEREEL
2004
Coumarins as serine protease inhibitors, in Drugs of the future, volume 29, issue A, pp. 171
Lionel POCHET, Raphael FRÉDÉRICK, Severine ROBERT, Stéphanie ROLIN, Bernard MASEREEL
2004
Insight into the mode of action of coumarins as thrombin inhibitors, in Fundamental and Clinical Pharmacology, volume 18, pp. 595
Raphael FRÉDÉRICK, Caroline CHARLIER, Jerome DE RUYCK, Marc DIEU, Severine ROBERT, Bernard MASEREEL, Lionel POCHET
2004
Coumarins as inhibitors of serine proteases of the coagulation cascade, in Drugs of the future, volume 29 , issue A, pp. 172
Raphael FRÉDÉRICK, Severine ROBERT, Caroline CHARLIER, Bernard MASEREEL, Lionel POCHET
2004
Synthesis and pharmacological evaluation of original thromboxane A2 receptor antagonists derived from BM-573., in Fundamental and Clinical Pharmacology, volume 18, pp. 593-599
Julien HANSON, Jean-François RENARD, Stéphanie ROLIN, Philippe NEVEN, Xavier DE LEVAL, Jean-Michel DOGNÉ, Bernard PIROTTE, Jean-Michel DOGNÉ
2003
Antithrombotic activity of BM-573, a novel thromboxane modulator, in rat arterial thrombosis model, pig myocardial infarction model and its effects on bleeding time, in Blood, volume November suppl, issue n°4213
Jean-Michel DOGNÉ, Philippe KOLH, Stéphanie ROLIN, Vincent TCHANA-SATO, Julien HANSON, Xavier DE LEVAL, Bernard LAMBERMONT, Alexandre GHUYSEN, Michel PÉTEIN, Laurence DE LEVAL, Bernard MASEREEL, Bernard PIROTTE
2003
A dual thromboxane inhibitor and thromboxane receptor antagonist prevents pig myocardial infarction induced by coronary thrombosis, in European Heart Journal, volume 24, pp. 325
Stéphanie ROLIN, Michel PÉTEIN, Vincent TCHANA-SATO, Jean-Michel DOGNÉ, Bernard LAMBERMONT, Alexandre GHUYSEN, Philippe KOLH, Bernard MASEREEL
2003
A dual thromboxane inhibitor and thromboxane receptor antagonist prevents pig myocardial infarction induced by coronary thrombosis, in Basic Research in Cardiology, volume 98, pp. 189
Stéphanie ROLIN, Michel PÉTEIN, Vincent TCHANA-SATO, Jean-Michel DOGNÉ, Bernard LAMBERMONT, Alexandre GHUYSEN, Philippe KOLH, Bernard MASEREEL
2003
Haemodynamic effect of thromboxane A2 inhibition in acute pulmonary embolism, in European Journal of Heart Failure, volume 2, issue 1, pp. 150
Alexandre GHUYSEN, Bernard LAMBERMONT, Philippe KOLH, Bernard MORIMONT, Vincent TCHANA-SATO, Jean-Michel DOGNÉ, Stéphanie ROLIN, Vincent D'ORIO
2003
BM-613, a new thromboxane A2 antagonist, is characterized by a preferential activity on platelet thromboxane a2 receptors, in Blood, volume November suppl, issue n°3013
Julien HANSON, Stéphanie ROLIN, Xavier DE LEVAL, Philippe NEVEN, Laurence DE LEVAL, Bernard MASEREEL, Bernard PIROTTE, Jean-Michel DOGNÉ
2002
Antithrombotic properties of BM-573 an original dual thromboxane receptor antagonist and thromboxane synthase inhibitor, in Pathophysiology of Haemostasis and Thrombosis, volume 32, issue (S2), pp. 60
Jean-Michel DOGNÉ, Patricia BENOIT, Xavier DE LEVAL, Stéphanie ROLIN, Philippe KOLH, Alexandre GHYSEN, Vincent TCHANA-SATO, Bernard MASEREEL
2002
Anti-platelet and antithrombotic properties of the nitrobenzenic sulfonylurea BM-573, in Fundamental and Clinical Pharmacology, volume 16, pp. 245
Jean-Michel DOGNÉ, Patricia BENOIT, Xavier DE LEVAL, Stéphanie ROLIN, Philippe NEVEN, Philippe KOLH, Bernard MASEREEL, Jean-Louis DAVID
2002
Design and pharmacological evaluation of a novel combined thromboxane A2 receptor antagonist and thromboxane synthase inhibitor derived from torasemide as promising antiplatelet agent, in Blood, volume 96, issue 11, pp. 230
Jean-Michel DOGNÉ, Xavier DE LEVAL , Stéphanie ROLIN, Philippe NEVEN, Philippe KOLH, Jean-Louis DAVID, G FILLET, Jacques DELARGE, Bernard MASEREEL
2001
Pharmacological evaluation of BM-573 an original dual thromboxane receptor antagonist and thromboxane synthase inhibitor as novel potent antithrombotic agent, in Blood, volume december, issue suppl
Jean-Michel DOGNÉ, Xavier DE LEVAL, Patricia BENOIT, Philippe NEVEN, Laurence DE LEVAL, Stéphanie ROLIN, Jean-Louis DAVID, Bernard MASEREEL
2001
Pharmacological evaluation of original sulfonylureas as thromboxane A2 antagonists, in Fundamental and Clinical Pharmacology, volume 300, pp. 14
Jean-Michel DOGNÉ, Xavier DE LEVAL, Philippe NEVEN, Fabian SOMERS, Jacques DELARGE, Stéphanie ROLIN, Catherine MICHAUX, Johan WOUTERS, Bernard PIROTTE, Jacques DAMAS, Bernard MASEREEL
2000
Characterization of the antiplatelet activity of ticlopidine and acetylsalicylic acid by PFA-100, in Fundamental and Clinical Pharmacology, volume 14, pp. 168
Jean-Michel DOGNÉ, Xavier DE LEVAL, Philipp NEVEN, Stéphanie ROLIN, Jean-Louis DAVID, Jacques DELARGE, Bernard MASEREEL
2000
Inhibition of cellular invasion by 3-chlorophenyl 6-(acétoxymethyl)-2-oxo-2H-1-benzopyran-3-carboxylate, in European Journal of Physiology, volume 440, issue 78, pp. R252
Isabelle KEMPEN, Lionel POCHET, D PAPAPOSTOLU, Nicole BOGETTO, Caroline DOUCET, Bernard MASEREEL, Jean-Michel FOIDART, Michèle REBOUD-RAVAUX, Francis FRANKENNE, Bernard PIROTTE
2000
Evaluation of classical NSAIDs on COX-1 and COX-2 purified enzymes and prognosis of their effects on physiological responses, in Fundamental and Clinical Pharmacology, volume 14, pp. 167
Xavier DE LEVAL, Yves HENROTIN, Bernard MASEREEL, Fabian SOMERS, Philippe NEVEN, Philippe DEVEL, Jacques DELARGE, Jean-Michel DOGNÉ
2000
BM-144, a novel thromboxane A2 receptor antagonist relaxes trachea guinea pig in vitro, in Journal of Allergy and Clinical Immunology, volume 105, pp. S21-S21
Jean-Michel DOGNÉ, Xavier DE LEVAL, Philippe NEVEN, Stéphanie ROLIN, Jacques DELARGE, Bernard MASEREEL
2000
Design, synthesis and pharmacological evalution of original thromboxane receptor antagonists., in Mediators of Inflammation, volume 9, pp. 53
Jean-Michel DOGNÉ, Xavier DE LEVAL, Jacques DELARGE, Jean-Yves REGINSTER, Yves HENROTTIN, Philippe NEVEN, Stéphanie ROLIN, Bernard MASEREEL
2000
Pharmacological evaluation of original sulfonylureas as thromboxane A2 antagonists, in Fundamental and clinical Pharmacology, volume 14, pp. 300
Jean-Michel DOGNÉ, Xavier DE LEVAL, Philippe NEVEN, Fabian SOMERS, Jacques DELARGE, Stéphanie ROLIN, Catherine MICHAUX, Johan WOUTERS, Bernard PIROTTE, Jacques DAMAS, Bernard MASEREEL
2000
Profile of nimesulide and nimesulide beta-cyclodextrin on chondrocyte metabolism., in Fundamental and Clinical Pharmacology, volume 14, pp. 169
Xavier DE LEVAL, Jean-Michel DOGNÉ, Bernard MASEREEL, Jean-Yves REGINSTER, Philippe NEVEN, A LABASSE, Jacques DELARGE, Yves HENROTIN
1999
PFA-100, a novel pharmacological tool for characterization of antiplatelet potency of thromboxane receptor antagonists, in Blood, volume 94 (suppl 1), pp. 3626
Jean-Michel DOGNÉ, Xavier DE LEVAL, Jacques DELARGE, Philippe NEVEN, Stéphanie ROLIN, Jean-Louis DAVID, Georges FILLET, Bernard MASEREEL
1998
Insulinotropic effect of glibenclamide isosteres, in Fundamental and Clinical Pharmacology, volume 12, pp. 307
Q.A. NGUYEN, Lionel POCHET, Raogo OUEDRAOGO, Mark J. DUNNE, Bernard MASEREEL, Philippe LEBRUN, Marie-Hélène ANTOINE

PHD theses

Student theses

2002
QCM en ligne
Christian POCHET

Student coursebooks

2007
Notes de Cours de Biochimie
Bernard MASEREEL
2007
Exercices de Technologie Pharmaceutique
Severine ROBERT, Jean-Michel DOGNÉ
2007
Note de cours d'Analyse Pharmaceutique
Bernard MASEREEL, Lionel POCHET
2006
Travaux Dirigés de Biochimie Générale
Severine ROBERT, Anne-Marie MURRAY, Bernard MASEREEL
2006
Séminaires de Biochimie Humaine
Severine ROBERT, Stéphanie ROLIN, Jean-Michel DOGNÉ
2005
Travaux Pratiques de Biochimie Générale
Severine ROBERT, Anne-Marie MURRAY, Bernard MASEREEL

Research reports

Multimedia

2010
Programme européen e-hematimage:Multiple myeloma
François MULLIER, Hassan MEKOUAR, Yvan CORNET, Bernard CHATELAIN
2009
Matériel et manipulations en labos pharmaceutiques [DVD]
Severine ROBERT, Philippe DEVEL, Julien DEGLIM, Bernard MASEREEL, Pauline SOVET, Didier LEPIÈCE, Monique NOIRHOMME-FRAITURE
2009
2008
Programme européen e-hematimage: Secondary ALL
François MULLIER, Bernard CHATELAIN